Sleep, interrupted – when short nights take their toll

Abstract

Sleep loss is increasingly recognized as a contributor to neuropathic pain, while diagnostic accuracy in thyroid carcinoma may be improved through refined assessment methods. In pediatric patients with cerebral palsy, transcranial magnetic stimulation (TMS) shows promise as a therapeutic intervention. Chronotherapy of blood pressure demonstrates how aligning antihypertensive treatment with circadian patterns may enhance efficacy. Artificial intelligence–based clinical decision support systems offer potential in the management of acute coronary syndromes, although current limitations and risks require careful consideration. Advances in precision oncology include comprehensive genomic profiling and spatial omics, while large language models highlight both opportunities and challenges in healthcare applications. Finally, age-related hormonal changes in combination with mitochondrial dysfunction are discussed in the context of carcinogenesis, underscoring the complex links between aging, metabolism, and cancer development.