Effects of physical exercise programs on fatigue and functional capacity in people with Guillain-Barré Syndrome and Chronic Inflammatory Demyelinating Polyneuropathy: A systematic review.
Alberto De León-Muñoz, Vicente Ávila-Gandía, Luis Andreu-Caravaca
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引用次数: 0
Abstract
Objective: To evaluate the impact of physical activity programs on fatigue and functional capacity, in addition to other variables related to patient's health in people suffering GBS and CIDP through a systematic review.
Data sources: Four databases (PubMed, Web of Science, Scopus and EBSCO) were searched according to PRISMA guidelines. The search was conducted from the inception until 01 of March 2025.
Data extraction: Data were extracted using Excel (v. 16051.17628.20144.0) and authors, country, year, study design, main variables, sample, intervention characteristics and primary outcomes of each article were used.
Study selection: Inclusion criteria focused on studies involving GBS and CIDP patients undergoing exercise programs lasting a minimum of three weeks. A total of 13 articles were analyzed (including case studies, randomized and no-randomized clinical trials, a prospective study, case series and a replicated single-case design), comprising 173 participants. Of these, five studies specifically included patients with CIDP, accounting for a total of 37 participants.
Data synthesis: The synthesis of the included studies indicates that multicomponent programs integrating resistance, aerobic, balance, and respiratory exercises are associated with improvements in fatigue and functional capacity, as well as other physical fitness variables. Furthermore, a pattern across the reviewed literature suggests that optimal results appear to be linked to supervised and individualized training sessions lasting 45-60 minutes, conducted 3-4 times per week for at least 12 weeks, although it must be noted that these findings were drawn from heterogeneous study designs.
Conclusions: Multicomponent exercise programmes appear to improve fatigue, functional capacity and physical fitness in patients with GBS and CIDP. Optimal benefits are associated with supervised and individualized sessions (45-60 minutes, 3-4 times per week for >12 weeks). These findings support structured training as a valuable component of these conditions.
目的:通过一项系统综述,评估体育活动计划对GBS和CIDP患者疲劳和功能能力的影响,以及与患者健康相关的其他变量。数据来源:根据PRISMA指南检索PubMed、Web of Science、Scopus和EBSCO四个数据库。搜寻工作从一开始就一直持续到2025年3月1日。数据提取:使用Excel (v. 16051.17628.20144.0)提取数据,采用每篇文章的作者、国家、年份、研究设计、主要变量、样本、干预特征和主要结局。研究选择:纳入标准集中在GBS和CIDP患者进行至少三周的运动项目的研究。共分析了13篇文章(包括病例研究、随机和非随机临床试验、一项前瞻性研究、病例系列和一项重复的单病例设计),包括173名参与者。其中,有5项研究专门纳入了CIDP患者,共37名参与者。数据综合:综合纳入的研究表明,包括阻力、有氧、平衡和呼吸运动在内的多组分计划与疲劳和功能能力的改善以及其他身体健康变量有关。此外,回顾文献的一个模式表明,最佳结果似乎与持续45-60分钟的监督和个性化训练课程有关,每周进行3-4次,持续至少12周,尽管必须注意这些发现来自异质研究设计。结论:多组分运动方案可以改善GBS和CIDP患者的疲劳、功能能力和体质。最佳效果与有监督和个性化的课程(45-60分钟,每周3-4次,持续12周)有关。这些发现支持结构化训练作为这些条件的一个有价值的组成部分。
期刊介绍:
The Archives of Physical Medicine and Rehabilitation publishes original, peer-reviewed research and clinical reports on important trends and developments in physical medicine and rehabilitation and related fields. This international journal brings researchers and clinicians authoritative information on the therapeutic utilization of physical, behavioral and pharmaceutical agents in providing comprehensive care for individuals with chronic illness and disabilities.
Archives began publication in 1920, publishes monthly, and is the official journal of the American Congress of Rehabilitation Medicine. Its papers are cited more often than any other rehabilitation journal.