Junhai Liu, Huan Duan, Hansheng Wang, Qi Gao, Lun Liu, Yinku Liang, Min He, Le Xu, Xiaosha Guo
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引用次数: 0
Abstract
Dandelion, a widely distributed medicinal plant, is rich in chlorogenic acid (CGA). However, research on the extraction and purification of CGA from dandelion, as well as its bioactivity, is insufficient. Therefore, this study developed an efficient and economic method for extracting CGA from dandelions using ultrasonic-assisted deep eutectic solvents. The DES system comprised betaine and oxalic acid, demonstrated high extraction efficiency, and was identified as the optimal extraction solvent. Furthermore, Response Surface Methodology (RSM) was employed to optimize the extraction conditions, which included: water content of 42 %, ultrasonic power of 300 W, ultrasonic temperature of 70 °C, ultrasonic time of 32 min, and solid-liquid ratio of 1:30 g/mL. Under these conditions, the extraction yield of CGA reached 4.27 mg/g. Dandelion samples treated with ultrasound-assisted DES had improved extraction efficiency. Following further purification with macroporous resin, the purified extract of CGA (PECGA) demonstrated significant antioxidant activity. Moreover, this ultrasonic-assisted PECGA showed considerable antibacterial efficacy against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli). This study provides evidence for potential applications of CGA extracted from dandelions as a natural antioxidant and antibacterial agent in the food and pharmaceutical industries.
期刊介绍:
Ultrasonics Sonochemistry stands as a premier international journal dedicated to the publication of high-quality research articles primarily focusing on chemical reactions and reactors induced by ultrasonic waves, known as sonochemistry. Beyond chemical reactions, the journal also welcomes contributions related to cavitation-induced events and processing, including sonoluminescence, and the transformation of materials on chemical, physical, and biological levels.
Since its inception in 1994, Ultrasonics Sonochemistry has consistently maintained a top ranking in the "Acoustics" category, reflecting its esteemed reputation in the field. The journal publishes exceptional papers covering various areas of ultrasonics and sonochemistry. Its contributions are highly regarded by both academia and industry stakeholders, demonstrating its relevance and impact in advancing research and innovation.