Chiral recognition via symmetry-dependent luminescence in zero-dimensional hybrid copper halides.

IF 15.7 1区综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES

Nature Communications Pub Date : 2025-10-02 DOI:10.1038/s41467-025-63835-y

Yi Wei,Yan Zhang,Yawen Li,Chen Li,Yuxuan Wang,Zhishan Luo,Yulian Liu,Huimin Kang,Xihan Chen,Zewei Quan

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Abstract

Chiral recognition through fluorescence changes enables the rapid and sensitive determination of enantiomers. However, the rational design and synthesis of fluorescent probes for efficient chiral recognition remain a challenge. Here we present a novel platform for chiral recognition based on zero-dimensional hybrid copper halides with unique symmetry-dependent properties. The use of mesomeric 1,2-diaminocyclohexane (DACH) ligands promotes the formation of centrosymmetric, non-luminescent Cu2I64- units. The incorporation of enantiopure S- or R-DACH ligands into these mesomeric compounds breaks their symmetry, spontaneously transforming them into chiral compounds and generating Cu4I62- units that exhibit intense circularly polarized luminescence. Additionally, introducing opposite chiral ligands into these chiral compounds leads to the formation of racemic, non-luminescent CuI32- units, whereas the addition of same-chirality ligands preserves the structure and optical properties of the chiral Cu4I62- units. This enantioselective response by utilizing symmetry-dependent optical properties offers a pathway toward advanced chiral sensing technologies.

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零维杂化卤化铜中对称性相关发光的手性识别。

通过荧光变化进行手性识别，可以快速、灵敏地测定对映体。然而，合理设计和合成有效的手性识别荧光探针仍然是一个挑战。本文提出了一种基于具有独特对称性的零维杂化卤化铜的手性识别新平台。1,2-二氨基环己烷（DACH）配体的使用促进了中心对称非发光Cu2I64-单元的形成。将对映纯S-或R-DACH配体掺入这些中间体化合物中，破坏了它们的对称性，自发地将它们转化为手性化合物，并生成具有强烈圆偏振发光的Cu4I62-单元。此外，在这些手性化合物中引入相反的手性配体会形成外消旋的、不发光的CuI32-单元，而加入相同手性的配体则保留了手性Cu4I62-单元的结构和光学性质。这种利用对称依赖光学特性的对映选择性反应为先进的手性传感技术提供了一条途径。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Communications Biological Science Disciplines-

CiteScore

24.90

自引率

2.40%

发文量

6928

审稿时长

3.7 months

期刊介绍： Nature Communications, an open-access journal, publishes high-quality research spanning all areas of the natural sciences. Papers featured in the journal showcase significant advances relevant to specialists in each respective field. With a 2-year impact factor of 16.6 (2022) and a median time of 8 days from submission to the first editorial decision, Nature Communications is committed to rapid dissemination of research findings. As a multidisciplinary journal, it welcomes contributions from biological, health, physical, chemical, Earth, social, mathematical, applied, and engineering sciences, aiming to highlight important breakthroughs within each domain.