Prehospital Vital Signs, Including SpO₂, Are Significantly Associated With Mortality and Mechanical Circulatory Support Requirement in Acute Myocardial Infarction Patients.

IF 3.7 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Circulation Journal Pub Date : 2025-09-30 DOI:10.1253/circj.CJ-25-0584

Tairo Kurita, Yumi Hirota, Hiroki Mori, Yosuke Kirii, Hiromasa Ito, Akihoro Takasaki, Keishi Moriwaki, Takeshi Takamura, Kozo Hoshino, Takashi Tanigawa, Tetsuya Kitamura, Norikazu Yamada, Kaoru Dohi

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引用次数: 0

Abstract

Background: Early risk stratification for acute myocardial infarction (AMI) using prehospital vital signs, including percutaneous oxygen before oxygen supply (pre-SpO₂), remains underexplored.

Methods and results: We analyzed 3,006 AMI patients from the Mie ACS Registry. Patients were stratified by the prehospital Simple Risk Index (pre-SRI = [heart rate × (age / 10)²] / systolic blood pressure) and pre-SpO₂levels. The primary outcome was 30-day death. Combined assessment of pre-SRI and pre-SpO₂was superior to individual parameters for predicting 30-day death. In the multivariate analysis, combined assessment (SRI ≥34 and SpO₂≤94%) was the strongest independent predictors of 30-day death (hazard ratio 3.98, P<0.001).

Conclusions: Prehospital vital signs including pre-SpO₂enable early high-risk identification, improving clinical decision-making for hospital selection.

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急性心肌梗死患者院前生命体征（包括SpO2）与死亡率和机械循环支持需求显著相关

背景：利用院前生命体征，包括供氧前经皮氧（pre-SpO2）进行急性心肌梗死（AMI）的早期风险分层，目前仍未得到充分探讨。方法和结果：我们分析了Mie ACS登记处的3006例AMI患者。采用院前简单风险指数（pre-SRI =[心率×（年龄/ 10）2]/收缩压）和院前spo2水平对患者进行分层。主要结局为30天死亡。在预测30天死亡方面，sri前和spo2前的综合评估优于单项参数。在多因素分析中，综合评估（SRI≥34,SpO2≤94%）是30天死亡的最强独立预测因子（风险比3.98,p）。结论：院前生命体征包括SpO2前可以早期识别高危人群，改善临床选择医院的决策。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Circulation Journal 医学-心血管系统

CiteScore

5.80

自引率

12.10%

发文量

471

审稿时长

1.6 months

期刊介绍： Circulation publishes original research manuscripts, review articles, and other content related to cardiovascular health and disease, including observational studies, clinical trials, epidemiology, health services and outcomes studies, and advances in basic and translational research.