Regional trends and disparities of lung cancer mortality in the United States, 1999-2022: a retrospective cohort study.

IF 5.8 2区医学 Q1 Medicine

Respiratory Research Pub Date : 2025-10-01 DOI:10.1186/s12931-025-03344-0

Taylor Billion, Logan Verheyen, Ali Bin Abdul Jabbar, Noureen Asghar, Mohsin Mirza, Muazzam Mirza, Abubakar Tauseef

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引用次数: 0

Abstract

Background: Lung cancer is the leading cause of cancer death in the US and worldwide. This study examines regional and state-level trends in lung cancer mortality in the US from 1999 to 2022.

Methods: Center for Disease Control and Prevention Wide-ranging Online Data for Epidemiologic Research (CDC WONDER) was used to obtain data on lung cancer mortality in people ages 25 years and older. Age-Adjusted Mortality Rate (AAMR) was calculated along with Annual Percent Change (APC) and Average Annual Percent Change (AAPC).

Results: In general, the age-adjusted mortality rate (AAMR) for lung cancer declined from 91.4 (95% CI 91.0 to 91.9) in 1999 to 52.0 (95% CI 51.7 to 52.2) in 2022. Throughout the study, the Midwest and South regions consistently exhibited the highest mortality rates. Notably, distinct patterns emerged when analyzing mortality rates by race and gender within each region.

Conclusion: This study revealed significant variations in lung cancer mortality at both regional and state levels. Recognizing these disparities is essential for healthcare policymakers and researchers to monitor progress in reducing lung cancer deaths and identifying the populations most vulnerable to this disease.

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1999-2022年美国肺癌死亡率的地区趋势和差异：一项回顾性队列研究

背景：肺癌是美国和世界范围内癌症死亡的主要原因。本研究调查了1999年至2022年美国肺癌死亡率的区域和州一级趋势。方法：使用疾病控制和预防中心流行病学研究广泛在线数据（CDC WONDER）获取25岁及以上人群肺癌死亡率的数据。年龄调整死亡率（AAMR）与年变化百分比（APC）和平均年变化百分比（AAPC）一起计算。结果：总体而言，肺癌的年龄调整死亡率（AAMR）从1999年的91.4 （95% CI 91.0 ~ 91.9）下降到2022年的52.0 （95% CI 51.7 ~ 52.2）。在整个研究过程中，中西部和南部地区一直表现出最高的死亡率。值得注意的是，在每个地区按种族和性别分析死亡率时，出现了不同的模式。结论：这项研究揭示了肺癌死亡率在地区和州水平上的显著差异。认识到这些差异对于卫生保健政策制定者和研究人员监测在减少肺癌死亡和确定最易患这种疾病的人群方面的进展至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Respiratory Research RESPIRATORY SYSTEM-

CiteScore

9.70

自引率

1.70%

发文量

314

审稿时长

4-8 weeks

期刊介绍： Respiratory Research publishes high-quality clinical and basic research, review and commentary articles on all aspects of respiratory medicine and related diseases. As the leading fully open access journal in the field, Respiratory Research provides an essential resource for pulmonologists, allergists, immunologists and other physicians, researchers, healthcare workers and medical students with worldwide dissemination of articles resulting in high visibility and generating international discussion. Topics of specific interest include asthma, chronic obstructive pulmonary disease, cystic fibrosis, genetics, infectious diseases, interstitial lung diseases, lung development, lung tumors, occupational and environmental factors, pulmonary circulation, pulmonary pharmacology and therapeutics, respiratory immunology, respiratory physiology, and sleep-related respiratory problems.