Factors Associated With Dizziness Among Patients With Vestibular Schwannoma.

IF 5.6 1区 医学 Q1 OTORHINOLARYNGOLOGY
Tyler Wilson, Dorina Kallogjeri, Belinda Sinks, Lauren English, Pawina Jiramongkolchai, Matthew Shew, Jacques Herzog, Craig Buchman, Jay Piccirillo, Nedim Durakovic
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引用次数: 0

Abstract

Importance: Patients with vestibular schwannoma (VS) commonly present with neurological symptoms such as hearing loss, tinnitus, and dizziness. However, factors associated with dizziness at presentation are not well understood.

Objective: To evaluate the baseline features of adults diagnosed with VS associated with subjective dizziness using a validated instrument.

Design, setting, and participants: This retrospective cohort study included adults with radiologically diagnosed VS who completed vestibular testing at Washington University (St Louis, Missouri) between June 2004 and January 2025. Baseline dizziness was measured using the Dizziness Handicap Inventory (DHI).

Exposures: Anxiety associated with a VS diagnosis.

Main outcomes and measures: The primary outcome was severity of dizziness based on DHI score.

Results: A total of 109 patients were included; the mean (SD) age was 61 (14) years, 57 (52%) were female, and 52 (48%) were male. The mean (SD) DHI score was 27 (24) points. Participants with a history of anxiety had a DHI score that was 13.7 points (95% CI, 4.2-23.2 points) higher than those with no such history. For every additional point in severity of anxiety measured using the Generalized Anxiety Disorder-7 (GAD-7) scale, DHI score increased 2.6 points (95% CI, 2.0-3.3 points). After controlling for covariates, for every 1-point increase in GAD-7, DHI score increased by a mean of 1.9 points (95% CI, 1.3-2.6 points). On average, patients with a history of anxiety had a DHI score 10.6 points (95% CI, 2.4-18.7 points) higher than those with no such history.

Conclusions and relevance: This retrospective cohort study suggests a psychological association between anxiety and dizziness might exist among patients with VS that has not previously been explored. Further studies examining this association are needed in this patient population.

前庭神经鞘瘤患者头晕的相关因素
重要性:前庭神经鞘瘤(VS)患者通常表现为神经系统症状,如听力丧失、耳鸣和头晕。然而,与出诊时头晕有关的因素尚不清楚。目的:用一种经过验证的仪器评估诊断为VS合并主观头晕的成人的基线特征。设计、环境和参与者:这项回顾性队列研究包括2004年6月至2025年1月在华盛顿大学(密苏里州圣路易斯)完成前庭测试的影像学诊断为VS的成年人。使用头晕障碍量表(DHI)测量基线头晕。暴露:与VS诊断相关的焦虑。主要结局和测量:主要结局是基于DHI评分的头晕严重程度。结果:共纳入109例患者;平均(SD)年龄61(14)岁,女性57(52%),男性52(48%)。DHI平均(SD)评分为27(24)分。有焦虑史的参与者的DHI得分比没有焦虑史的参与者高13.7分(95% CI, 4.2-23.2分)。使用广泛性焦虑障碍-7 (GAD-7)量表测量的焦虑严重程度每增加1分,DHI得分增加2.6分(95% CI, 2.0-3.3分)。在控制协变量后,GAD-7每增加1分,DHI评分平均增加1.9分(95% CI, 1.3-2.6分)。平均而言,有焦虑史的患者DHI得分比无焦虑史的患者高10.6分(95% CI, 2.4-18.7分)。结论和相关性:这项回顾性队列研究表明,焦虑和头晕之间的心理联系可能存在于VS患者中,这在以前没有被探索过。需要在该患者群体中进一步研究这种关联。
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来源期刊
CiteScore
9.10
自引率
5.10%
发文量
230
期刊介绍: JAMA Otolaryngology–Head & Neck Surgery is a globally recognized and peer-reviewed medical journal dedicated to providing up-to-date information on diseases affecting the head and neck. It originated in 1925 as Archives of Otolaryngology and currently serves as the official publication for the American Head and Neck Society. As part of the prestigious JAMA Network, a collection of reputable general medical and specialty publications, it ensures the highest standards of research and expertise. Physicians and scientists worldwide rely on JAMA Otolaryngology–Head & Neck Surgery for invaluable insights in this specialized field.
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