Semiheterogeneous Intrinsic FeTiO3-Photoredox/Ph3N Dual-Catalyzed Fluoroalkylation of N-Heteroarenes with Alkenes and RfSO2Cl

Abstract

Herein, we report the sustainable semiheterogeneous synthesis of various fluoroalkylated N-heteroarenes using natural intrinsic iron(II) titanium oxide (FeTiO₃) as a semiconductor photocatalyst and Ph₃N as a redox mediator. This synergistic system combines photogenerated electron-mediated fluoroalkyl sulfonyl chloride (R_fSO₂Cl) reduction with photogenerated hole-induced oxidative dehydrogenation aromatization, enabling high-yielding transformations with excellent functional-group tolerance while avoiding stoichiometric redox reagents or sacrificial electron donors/acceptors.