Vaccine Induced Seroreactivity Following Administration of ALVAC-HIV/AIDSVAX®B/E Identified by Common Anti-HIV Test Kits and Algorithms in Thailand.

IF 3.8 4区医学 Q2 IMMUNOLOGY

Open Forum Infectious Diseases Pub Date : 2025-09-16 eCollection Date: 2025-10-01 DOI:10.1093/ofid/ofaf578

Siriwat Akapirat, Elisavet Serti, Punnee Pitisutthithum, Sorachai Nitayaphan, Suwat Chariyalertsak, Chirapa Eamsila, Pornchanok Panjapornsuk, Anocha Kleebmontha, Somsak Chantakulkij, Bhubate Tongchanakarn, Hathairat Savadsuk, Jittima Dhitavat, Sanjay Gurunathan, Faruk Sinangil, Trevor A Crowell, Nelson L Michael, Merlin L Robb, Sandhya Vasan, Robert J O'Connell

引用次数: 0

Abstract

Vaccine-induced seroreactivity (VISR) was evaluated in RV306 and was shown to vary markedly (0-32.5%) among 6 HIV diagnostic tests and 84 algorithms. Our data show that selecting the SD Bioline HIV-1/2 assay and algorithms which exclude the ImmunoComb®II Bispot and Alere™ Determine HIV-1/2 assays would almost eliminate VISR in RV306.

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泰国常用抗hiv检测试剂盒和算法鉴定的ALVAC-HIV/AIDSVAX®B/E疫苗诱导的血清反应性

在RV306中评估了疫苗诱导的血清反应性（VISR），并显示在6种HIV诊断检测和84种算法中差异显著（0-32.5%）。我们的数据显示，选择SD Bioline HIV-1/2检测和排除ImmunoComb®II Bispot和Alere™Determine HIV-1/2检测的算法几乎可以消除RV306中的VISR。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Open Forum Infectious Diseases Medicine-Neurology (clinical)

CiteScore

6.70

自引率

4.80%

发文量

630

审稿时长

9 weeks

期刊介绍： Open Forum Infectious Diseases provides a global forum for the publication of clinical, translational, and basic research findings in a fully open access, online journal environment. The journal reflects the broad diversity of the field of infectious diseases, and focuses on the intersection of biomedical science and clinical practice, with a particular emphasis on knowledge that holds the potential to improve patient care in populations around the world. Fully peer-reviewed, OFID supports the international community of infectious diseases experts by providing a venue for articles that further the understanding of all aspects of infectious diseases.