FIGO committee opinion: Environmental drivers of obstetric health and early childhood development.

IF 2.4 3区 医学 Q2 OBSTETRICS & GYNECOLOGY
Nathaniel DeNicola, Emily Lasher, Abena BakenRa, Rashmi Joglekar, Jun Zhang, Annette Hasenburg, Krishnendu Gupta, Ditas Decena, Francisco Edna, David Graham, Edward Morris, Blami Dao, Tracey Woodruff
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引用次数: 0

Abstract

Environmental exposures are increasingly recognized as critical, yet underappreciated, determinants of reproductive, perinatal, and early childhood health. Developed through a structured consensus process and grounded in systematic evidence review, this FIGO committee opinion provides a comprehensive synthesis of the current evidence linking environmental toxicants-including air pollution, endocrine-disrupting chemicals, heavy metals, and climate-related stressors-to common obstetric outcomes such as preterm birth, hypertensive disorders of pregnancy, gestational diabetes, and impaired fetal growth, as well as to early childhood outcomes including neurodevelopmental delay, metabolic disease, and atopic conditions. This article also outlines common biological mechanisms, such as endocrine disruption, oxidative stress, epigenetic modification, and placental dysfunction, and provides clinicians with actionable guidance for integrating environmental health into reproductive care through screening, counseling, and advocacy. Special attention is paid to the role of social and structural inequities in amplifying exposure risks and health disparities. By linking environmental drivers to familiar clinical outcomes, this guidance empowers obstetricians and allied professionals to engage in preventive care that safeguards maternal and child health across the life course. FIGO calls on reproductive health professionals to embrace this leadership role-not only in clinical practice, but in shaping policies that protect current and future generations.

FIGO委员会意见:产科保健和幼儿发展的环境驱动因素。
环境暴露日益被认为是生殖、围产期和幼儿健康的关键决定因素,但未得到充分重视。这份FIGO委员会意见是通过结构化的共识过程制定的,以系统的证据审查为基础,全面综合了目前将环境毒物(包括空气污染、内分泌干扰化学物质、重金属和气候相关压力源)与常见产科结局(如早产、妊娠高血压疾病、妊娠糖尿病和胎儿生长受损)联系起来的证据。以及早期儿童结果,包括神经发育迟缓,代谢疾病和特应性疾病。本文还概述了常见的生物学机制,如内分泌紊乱、氧化应激、表观遗传修饰和胎盘功能障碍,并为临床医生提供了可操作的指导,通过筛查、咨询和宣传将环境健康纳入生殖保健。特别注意社会和结构不平等在扩大接触风险和健康差距方面的作用。通过将环境驱动因素与熟悉的临床结果联系起来,本指南使产科医生和相关专业人员能够从事预防保健,在整个生命过程中保障孕产妇和儿童健康。FIGO呼吁生殖健康专业人员不仅在临床实践中发挥领导作用,而且在制定保护当代人和子孙后代的政策方面发挥领导作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
5.80
自引率
2.60%
发文量
493
审稿时长
3-6 weeks
期刊介绍: The International Journal of Gynecology & Obstetrics publishes articles on all aspects of basic and clinical research in the fields of obstetrics and gynecology and related subjects, with emphasis on matters of worldwide interest.
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