Food and Mood: Current Evidence on Mental Health and the Microbiota-Gut-Brain Axis.

IF 6.7 2区医学 Q1 PSYCHIATRY

Current Psychiatry Reports Pub Date : 2025-11-01 Epub Date: 2025-09-30 DOI:10.1007/s11920-025-01636-2

Meroë B Morse, Bianca Garcia

{"title":"Food and Mood: Current Evidence on Mental Health and the Microbiota-Gut-Brain Axis.","authors":"Meroë B Morse, Bianca Garcia","doi":"10.1007/s11920-025-01636-2","DOIUrl":null,"url":null,"abstract":"Purpose of review: Depression and anxiety are among the most common global mental health conditions. Emerging research highlights the impact of diet and the gut microbiome on the nervous system and mood. We review and discuss the existing research on the effects of various diets-including high-fiber, fermented, ketogenic, and calorie-restricted diets-alongside the roles of prebiotics and probiotics, on anxiety and depression.Recent findings: While mostly observational, mounting data from randomized controlled trials support the idea that dietary modification can improve mental health outcomes by altering gut microbial composition and activity. The efficacy of supplements and probiotics in mood outcomes is conflicting. Additional research is needed to fully understand the mechanisms that link diet, the gut microbiome, and mental health. Overall, findings suggest that dietary modifications are feasible and beneficial in mild cases of anxiety and depression. This review explores the bidirectional relationship between diet, gut microbiome, and mood disorders. Various diets are discussed, and their respective impact on mental health is reviewed. Challenges in food and mood research remain due to variability in research practices. Additional studies are needed to further explore the role of nutrition in optimizing mental health.","PeriodicalId":11057,"journal":{"name":"Current Psychiatry Reports","volume":" ","pages":"632-641"},"PeriodicalIF":6.7000,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Psychiatry Reports","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s11920-025-01636-2","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/9/30 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"PSYCHIATRY","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose of review: Depression and anxiety are among the most common global mental health conditions. Emerging research highlights the impact of diet and the gut microbiome on the nervous system and mood. We review and discuss the existing research on the effects of various diets-including high-fiber, fermented, ketogenic, and calorie-restricted diets-alongside the roles of prebiotics and probiotics, on anxiety and depression.

Recent findings: While mostly observational, mounting data from randomized controlled trials support the idea that dietary modification can improve mental health outcomes by altering gut microbial composition and activity. The efficacy of supplements and probiotics in mood outcomes is conflicting. Additional research is needed to fully understand the mechanisms that link diet, the gut microbiome, and mental health. Overall, findings suggest that dietary modifications are feasible and beneficial in mild cases of anxiety and depression. This review explores the bidirectional relationship between diet, gut microbiome, and mood disorders. Various diets are discussed, and their respective impact on mental health is reviewed. Challenges in food and mood research remain due to variability in research practices. Additional studies are needed to further explore the role of nutrition in optimizing mental health.

查看原文本刊更多论文

食物和情绪：心理健康和微生物-肠-脑轴的最新证据。

综述目的：抑郁和焦虑是全球最常见的精神健康状况。新兴研究强调了饮食和肠道微生物群对神经系统和情绪的影响。我们回顾并讨论了各种饮食（包括高纤维饮食、发酵饮食、生酮饮食和限制热量饮食）对焦虑和抑郁的影响，以及益生元和益生菌的作用。最近的发现：虽然大多是观察性的，但越来越多的随机对照试验数据支持这样一种观点，即饮食调整可以通过改变肠道微生物组成和活动来改善心理健康状况。补充剂和益生菌对情绪结果的功效是相互矛盾的。需要进一步的研究来充分了解饮食、肠道微生物群和心理健康之间的联系机制。总的来说，研究结果表明，在轻度焦虑和抑郁病例中，饮食调整是可行和有益的。这篇综述探讨了饮食、肠道微生物群和情绪障碍之间的双向关系。讨论了各种饮食，并回顾了它们各自对心理健康的影响。由于研究实践的可变性，食物和情绪研究中的挑战仍然存在。需要进一步的研究来进一步探索营养在优化心理健康中的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Current Psychiatry Reports PSYCHIATRY-

CiteScore

11.30

自引率

3.00%

发文量

审稿时长

6-12 weeks

期刊介绍： This journal aims to review the most important, recently published research in psychiatry. By providing clear, insightful, balanced contributions by international experts, the journal intends to serve all those involved in the care of those affected by psychiatric disorders. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as anxiety, medicopsychiatric disorders, and schizophrenia and other related psychotic disorders. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.