Clinical factors associated with radiographic severity of progressive temporomandibular joint osteoarthritis: a retrospective CBCT study.

IF 2.4 3区医学 Q2 ORTHOPEDICS

BMC Musculoskeletal Disorders Pub Date : 2025-09-30 DOI:10.1186/s12891-025-09149-y

Rüdiger Emshoff, Ansgar Rudisch, Stefan Bertram

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引用次数: 0

Abstract

Background: Temporomandibular joint (TMJ) osteoarthritis (OA) is a progressive deteriorative joint disorder characterized by loss of cartilage and alterations in subchondral bone architecture. The study aimed to identify clinical baseline parameters most closely associated with radiographic indicators of deteriorative OA severity.

Methods: The study consisted of 233 patients with unilateral TMJ arthralgia (204 females, 29 males; mean age 41.9 ± 18.1 years) meeting the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) Axis I. Following clinical examination, each patient underwent cone beam computed tomography (CBCT) evaluation of both TMJs. A composite subchondral bone alteration (SBA) grading score of progressive deteriorative OA changes was used including the following items: erosion, resorption, cyst, sclerosis, osteophyte, and flattening; the maximum possible score was 4.

Results: Multivariate ordinal regression analysis identified the following factors significantly associated with the severity of condylar SBAs: older age (> 45 years) (odds ratio [OR], 4.53; p < 0.001), having concomitant arthralgia (OR, 1.85; p = 0.035), and higher number of condylar side-related missing posterior teeth (> 4) (OR, 1.80; p = 0.039).

Conclusions: The data Suggest that patients older than 45 years who have a concurrent arthralgia, and missing more than 4 posterior teeth may have an increased risk of developing progressive SBAs. By focusing on these clinical factors, patients should be advised of their heightened risk of developing deteriorative SBAs to avoid delayed diagnosis and treatment. Ongoing research is warranted to improve the model, and prove the validity and reliability of the model.

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与进行性颞下颌关节骨关节炎放射学严重程度相关的临床因素：回顾性CBCT研究。

背景：颞下颌关节（TMJ）骨关节炎（OA）是一种进行性恶化的关节疾病，其特征是软骨丢失和软骨下骨结构的改变。该研究旨在确定与恶化性OA严重程度的影像学指标最密切相关的临床基线参数。方法：本研究纳入233例单侧颞下颌关节痛患者（女性204例，男性29例，平均年龄41.9±18.1岁），符合颞下颌关节疾病诊断标准（DC/TMD）轴i。临床检查后，每位患者均接受锥形束计算机断层扫描（CBCT）评估双侧颞下颌关节。采用软骨下骨改变（SBA）复合评分法对进行性骨性关节炎进行评分，评分项目包括：侵蚀、吸收、囊肿、硬化、骨赘和变平；最高可得4分。结果：多因素有序回归分析发现以下因素与髁突SBAs的严重程度显著相关：年龄较大（45岁）（比值比[OR]， 4.53; p 4）（OR, 1.80; p = 0.039）。结论：数据提示年龄大于45岁并发关节痛且缺失4颗以上后牙的患者发生进行性SBAs的风险增加。通过关注这些临床因素，应告知患者发展为恶化性SBAs的高风险，以避免延误诊断和治疗。需要进一步的研究来改进模型，并证明模型的有效性和可靠性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BMC Musculoskeletal Disorders 医学-风湿病学

CiteScore

3.80

自引率

8.70%

发文量

1017

审稿时长

3-6 weeks

期刊介绍： BMC Musculoskeletal Disorders is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of musculoskeletal disorders, as well as related molecular genetics, pathophysiology, and epidemiology. The scope of the Journal covers research into rheumatic diseases where the primary focus relates specifically to a component(s) of the musculoskeletal system.