Supramolecular Assembly and Interfacial Hydration of Tandem Repeat Dipeptides on 2D Nanomaterials: Insights From 3D-AFM Measurements and MD Simulations (Small 39/2025)

IF 12.1 2区材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Small Pub Date : 2025-10-02 DOI:10.1002/smll.70299

Ayhan Yurtsever, Fabio Priante, Linhao Sun, Marie Sugiyama, Kazuki Miyata, Keisuke Miyazawa, Sanhanut Kesornsit, Katsuhiro Maeda, Adam S. Foster, Yuhei Hayamizu, Mehmet Sarikaya, Takeshi Fukuma

引用次数: 0

Abstract

Bionanomaterials

In article number 2501785, Ayhan Yurtsever, Linhao Sun, Yuhei Hayamizu, Takeshi Fukuma, and co-workers investigate Tyr-His (YH) dipeptide tandem repeats assembled on cleaved graphite and MoS₂ substrates. The study reveals how 3D hydration shells govern peptide nanoarchitecture assembly, with molecular visualization showing peptides adopt fully extended, linear conformations aligned with specific crystallographic orientations. The lengths of assembled peptides match their unfolded states, including hydration layers.

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二维纳米材料上串联重复二肽的超分子组装和界面水合作用：来自3D-AFM测量和MD模拟的见解（Small 39/2025）

在文章编号2501785中，Ayhan Yurtsever, Linhao Sun, Yuhei Hayamizu， Takeshi Fukuma等研究了在裂解石墨和MoS2底物上组装的Tyr-His （YH）二肽串联重复序列。该研究揭示了3D水合壳如何控制肽纳米结构组装，分子可视化显示肽采用完全延伸的线性构象，与特定的晶体学取向对齐。组装肽的长度与其未展开的状态相匹配，包括水合层。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Small 工程技术-材料科学：综合

CiteScore

17.70

自引率

3.80%

发文量

1830

审稿时长

2.1 months

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