Optical Fiber Sensor with Dynamically Responsive Cladding for Real-Time Breath Pattern Monitoring

IF 4.3 3区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY
ACS Omega Pub Date : 2025-09-19 DOI:10.1021/acsomega.5c06598
Pillalamarri Srikrishnarka, , , Jani Patrakka, , , Zhipei Sun, , and ,  Nonappa*, 
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Abstract

Rapid and real-time monitoring of humidity changes is critical, as they impact human health, material storage, and stability, industrial fabrication, microbial transmission, and agriculture. In recent years, optical fiber-based sensors have emerged as promising candidates for monitoring exhaled and inhaled breath humidity to assess respiratory rate, with the goal of supporting clinical diagnosis and patient care. Conventional multimode plastic optical fibers utilize a high refractive index core and lower refractive index cladding for effective total internal reflection (TIR) to achieve waveguiding. In contrast, here, we fabricated an optical fiber-based sensor with a higher refractive index (1.52) biopolymer-based cladding onto a lower refractive index (1.49) poly(methyl methacrylate) (PMMA) core. We demonstrate that the cladding dynamically responds to a rapid humidity change by altering the refractive index and improving the TIR, allowing real-time humidity monitoring. Our results show that the sensitivity was characterized by a second-order polynomial fit, with a sensitivity of 0.18 dB/%RH (in the range of 40–70% RH) and an overall attenuation reduction of 9.4 dB at 70% RH. A proof-of-concept device, by ready integration of a fiber into a miniaturized platform, allowed for rapid and real-time exhaled breath humidity detection and differentiation of nasal and oral breathing patterns with a time resolution of 1.3 s. Notably, the device does not exhibit saturation under high humidity conditions, suggesting the robustness and enormous potential of optical fiber-based humidity sensors for long-term breath humidity monitoring, early detection of abnormal breath patterns, and deployment in next-generation healthcare monitoring.

动态响应包层光纤传感器用于实时呼吸模式监测
快速实时监测湿度变化至关重要,因为它们影响人类健康、材料储存和稳定性、工业制造、微生物传播和农业。近年来,基于光纤的传感器已成为监测呼出和吸入呼吸湿度以评估呼吸速率的有希望的候选者,其目标是支持临床诊断和患者护理。传统的多模塑料光纤利用高折射率的纤芯和低折射率的包层来实现有效的全内反射(TIR),从而实现波导。相比之下,我们在这里制造了一种基于光纤的传感器,该传感器具有高折射率(1.52)的生物聚合物包层,覆盖在低折射率(1.49)的聚甲基丙烯酸甲酯(PMMA)核心上。我们证明了包层通过改变折射率和提高TIR来动态响应快速的湿度变化,从而实现实时湿度监测。我们的研究结果表明,灵敏度符合二阶多项式拟合,灵敏度为0.18 dB/%RH(在40-70% RH范围内),70% RH时的总体衰减降低了9.4 dB。一种概念验证设备,通过将光纤集成到一个小型化的平台上,可以快速实时地检测呼气湿度,并以1.3秒的时间分辨率区分鼻腔和口腔呼吸模式。值得注意的是,该设备在高湿度条件下不会出现饱和,这表明基于光纤的湿度传感器在长期呼吸湿度监测、早期检测异常呼吸模式和部署下一代医疗保健监测方面具有坚固性和巨大潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
ACS Omega
ACS Omega Chemical Engineering-General Chemical Engineering
CiteScore
6.60
自引率
4.90%
发文量
3945
审稿时长
2.4 months
期刊介绍: ACS Omega is an open-access global publication for scientific articles that describe new findings in chemistry and interfacing areas of science, without any perceived evaluation of immediate impact.
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