Impact of Lifestyle Activity Engagement on Incident Disability: A Stratified Analysis by Cardiovascular Disease Risk.

IF 4 3区 医学 Q2 CLINICAL NEUROLOGY
Fumio Sakimoto, Takehiko Doi, Sho Nakakubo, Soichiro Matsuda, Keitaro Makino, Hiroyuki Shimada
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Abstract

Introduction: Cardiovascular disease (CVD) is associated with disability, highlighting the need for prevention strategies that assess and mitigate CVD risk. This study aimed to examine the relationship between participation in lifestyle activities and incident disability among older individuals at high risk of CVD.

Methods: This prospective cohort study included 3,217 older adults (mean age 70.7 years, standard deviation ± 6.8; 1,843 women [57.3%]). Absolute CVD risk was estimated using the revised World Health Organization charts, categorizing individuals' risk levels as either low (< 10%) or high (≥ 10%). The incidence of disability was monitored for 60 months. Baseline assessments included the frequency of participation in 36 lifestyle activities spanning physical, cognitive, and social domains, measured by annual participation frequency. A total score was calculated and categorized into three tertiles based on the frequency of participation (low, moderate, and high groups). An adjusted Cox proportional hazard analysis assessed disability risk based on baseline participation in lifestyle activities stratified by CVD risk level.

Results: Over 60 months, 326 participants (10.2%) experienced disability. Older adults who were highly active in cognitive and social activities had a lower risk of disability than those who were less active. Stratified analysis based on CVD risk level showed that engagement in lifestyle activities was linked to disability risk among older adults at high risk of CVD, whereas no such association was observed in those at low risk.

Conclusion: Among older adults at high CVD risk, greater engagement in lifestyle activities was associated with a reduced risk of disability after 60 months.

生活方式活动参与对意外残疾的影响:心血管疾病风险的分层分析
导论:心血管疾病(CVD)与残疾相关,强调了评估和减轻CVD风险的预防策略的必要性。本研究旨在探讨心血管疾病高风险的老年人参与生活方式活动与意外残疾之间的关系。方法:该前瞻性队列研究纳入3217名老年人(平均年龄70.7岁,标准差±6.8;1,843名女性[57.3%])。使用修订后的世界卫生组织图表估计绝对心血管疾病风险,将个体风险水平分为低(< 10%)和高(≥10%)。残疾发生率监测60个月。基线评估包括参与36种生活方式活动的频率,包括身体、认知和社会领域,以年参与频率衡量。计算总分,并根据参与频率(低、中、高组)将其分为三类。调整后的Cox比例风险分析评估了以心血管疾病风险水平分层的生活方式活动基线参与程度为基础的残疾风险。结果:超过60个月,326名参与者(10.2%)经历了残疾。在认知和社会活动中高度活跃的老年人比那些不太活跃的老年人患残疾的风险更低。基于心血管疾病风险水平的分层分析显示,在心血管疾病高风险的老年人中,参与生活方式活动与残疾风险相关,而在低风险的老年人中没有观察到这种关联。结论:在心血管疾病高风险的老年人中,更多地参与生活方式活动与60个月后残疾风险降低相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Neuroepidemiology
Neuroepidemiology 医学-公共卫生、环境卫生与职业卫生
CiteScore
9.90
自引率
1.80%
发文量
49
审稿时长
6-12 weeks
期刊介绍: ''Neuroepidemiology'' is the only internationally recognised peer-reviewed periodical devoted to descriptive, analytical and experimental studies in the epidemiology of neurologic disease. The scope of the journal expands the boundaries of traditional clinical neurology by providing new insights regarding the etiology, determinants, distribution, management and prevention of diseases of the nervous system.
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