Associations between slow-wave sleep and dementia: a systematic review.

Q3 Medicine

East Asian Archives of Psychiatry Pub Date : 2025-09-01 DOI:10.12809/eaap2577

N Zeng, R J Y Hew, K Cao, Y Z Ng, J V Yeap, B L Nguyen, C T Tang, S M Tan

{"title":"Associations between slow-wave sleep and dementia: a systematic review.","authors":"N Zeng, R J Y Hew, K Cao, Y Z Ng, J V Yeap, B L Nguyen, C T Tang, S M Tan","doi":"10.12809/eaap2577","DOIUrl":null,"url":null,"abstract":"Objective: To conduct a systematic review of the literature to examine the associations between slowwave sleep (SWS) disturbance and dementia.Methods: We systematically searched PubMed and Embase for cohort and case-control studies that examined SWS differences between patients with dementia and healthy controls. Study quality was assessed using the Newcastle-Ottawa Scale.Results: In total, 19 studies (three cohort and 16 case-control) were included in analysis. Overall, one cohort study and 14 case-control studies found that reduced SWS was associated with dementia; the evidence was stronger in case-control studies than cohort studies. Study quality of studies varied; most were above average.Conclusion: Most studies regarding the association between SWS and dementia are cross-sectional; more longitudinal studies are needed to determine whether reduction in SWS can predict incident dementia. Future studies should include multi-night recordings and the use of standardised criteria to enhance the accuracy of recordings and facilitate comparisons between studies.","PeriodicalId":39171,"journal":{"name":"East Asian Archives of Psychiatry","volume":"35 3","pages":"194-201"},"PeriodicalIF":0.0000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"East Asian Archives of Psychiatry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.12809/eaap2577","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: To conduct a systematic review of the literature to examine the associations between slowwave sleep (SWS) disturbance and dementia.

Methods: We systematically searched PubMed and Embase for cohort and case-control studies that examined SWS differences between patients with dementia and healthy controls. Study quality was assessed using the Newcastle-Ottawa Scale.

Results: In total, 19 studies (three cohort and 16 case-control) were included in analysis. Overall, one cohort study and 14 case-control studies found that reduced SWS was associated with dementia; the evidence was stronger in case-control studies than cohort studies. Study quality of studies varied; most were above average.

Conclusion: Most studies regarding the association between SWS and dementia are cross-sectional; more longitudinal studies are needed to determine whether reduction in SWS can predict incident dementia. Future studies should include multi-night recordings and the use of standardised criteria to enhance the accuracy of recordings and facilitate comparisons between studies.

查看原文本刊更多论文

慢波睡眠和痴呆之间的关系：一项系统综述。

目的：对慢波睡眠障碍与痴呆之间的关系进行系统的文献综述。方法：我们系统地检索了PubMed和Embase的队列和病例对照研究，以检查痴呆患者和健康对照组之间的SWS差异。使用纽卡斯尔-渥太华量表评估研究质量。结果：共纳入19项研究（3项队列研究和16项病例对照研究）。总体而言，一项队列研究和14项病例对照研究发现，SWS降低与痴呆有关；病例对照研究的证据比队列研究更有力。研究质量参差不齐；大多数人的成绩高于平均水平。结论：大多数关于SWS与痴呆关系的研究都是横断面的；需要更多的纵向研究来确定SWS的减少是否可以预测痴呆的发生。未来的研究应包括多夜记录和使用标准化标准，以提高记录的准确性和促进研究之间的比较。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

East Asian Archives of Psychiatry Medicine-Medicine (all)

CiteScore

1.60

自引率

0.00%

发文量