Optimizing postoperative infection control strategies in gastrointestinal surgery via integrated disinfection, isolation measures, and risk prediction models.

IF 1.7 4区 医学 Q3 GASTROENTEROLOGY & HEPATOLOGY
Qin-Zhi Liu, Lei Zeng, Nian-Zhe Sun
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Abstract

This editorial critically evaluated the recent study by Wang et al, which systematically investigated the efficacy of perioperative disinfection and isolation measures (including preoperative povidone-iodine disinfection, intraoperative sterile barrier techniques, and postoperative intensive care) in reducing infection rates. The study further incorporated the surgical site infection risk prediction model (constructed via the least absolute shrinkage and selection operator algorithm, integrating patients' baseline characteristics, surgical indicators, and regional antibiotic-resistant bacterial data), and proposed a dynamic prevention and control system termed "disinfection protocols-predictive models-real-time monitoring". The article highlighted that preoperative risk stratification, intraoperative personalized antibiotic selection, and postoperative multidimensional monitoring (encompassing inflammatory biomarkers, imaging, and microbiological testing) enabled the precise identification of high-risk patients and optimized intervention thresholds. Future research is deemed necessary to validate the synergistic effects of disinfection protocols and predictive models through large-scale multicenter studies, combined with advanced intraoperative rapid microbial detection technologies. This approach aims to establish standardized infection control protocols tailored for precision medicine and regional adaptability. Future research should prioritize validating the synergistic effects of disinfection protocols and predictive models via multi-center studies, while incorporating advanced rapid intraoperative microbial detection technologies to develop standardized infection prevention and control procedures. Such efforts will enhance the implementation of precise and regionally adaptive infection control strategies.

通过综合消毒、隔离措施和风险预测模型优化胃肠道手术术后感染控制策略。
这篇社论批判性地评价了Wang等人最近的研究,该研究系统地调查了围手术期消毒和隔离措施(包括术前聚维酮碘消毒、术中无菌屏障技术和术后重症监护)在降低感染率方面的效果。本研究进一步纳入手术部位感染风险预测模型(通过最小绝对收缩和选择算子算法构建,综合患者基线特征、手术指标和区域耐药菌数据),提出了“消毒方案-预测模型-实时监测”的动态防控系统。文章强调,术前风险分层、术中个性化抗生素选择和术后多维监测(包括炎症生物标志物、影像学和微生物检测)可以精确识别高危患者并优化干预阈值。未来的研究需要通过大规模的多中心研究,结合先进的术中快速微生物检测技术,来验证消毒方案和预测模型的协同效应。该方法旨在建立适合精准医疗和区域适应性的标准化感染控制方案。未来的研究应优先通过多中心研究验证消毒方案和预测模型的协同效应,同时结合先进的快速术中微生物检测技术,制定标准化的感染预防和控制程序。这些努力将加强实施精确的和适合区域的感染控制战略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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