Fetoscopic Laser Ablation of Type II Vasa Previa-Case Report and Systematic Review.

IF 2.7 2区 医学 Q2 GENETICS & HEREDITY
Prenatal Diagnosis Pub Date : 2025-09-29 DOI:10.1002/pd.6897
Rodrigo Ruano, Olivia Mihulka, Aishu Hombal, Natalia Ravelo, Lara Slesnick, Ugo Maria Pierucci
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引用次数: 0

Abstract

Vasa previa is a rare but potentially fatal obstetric condition in which fetal vessels traverse the internal cervical os without the protection of placental tissue or Wharton's jelly, making them highly vulnerable to rupture during labor or spontaneous membrane rupture. This can result in rapid fetal exsanguination and death. While current management involves planned cesarean delivery before the onset of labor, fetoscopic laser ablation (FLA) has recently emerged as a minimally invasive alternative for selected cases, particularly type II and III vasa previa, allowing for pregnancy prolongation and potential vaginal delivery. We report the case of a 40-year-old gravida 3 para 0 woman diagnosed with type II vasa previa at 22 + 5 weeks. FLA was performed successfully at 31 + 5 weeks without complications. At 36 + 5 weeks, she experienced spontaneous rupture of membranes and delivered a healthy male neonate via cesarean section at maternal request. To contextualize this case, we conducted a systematic review of 54 cases from the literature. FLA was associated with a 98.1% technical success rate, 50% vaginal delivery rate, and 100% neonatal survival, with no major maternal complications reported. These findings suggest that FLA may offer a safe and effective alternative to preterm cesarean delivery in selected patients.

胎儿镜激光消融II型前置血管一例报告及系统回顾。
前置瓦萨是一种罕见但潜在致命的产科疾病,胎儿血管在没有胎盘组织或华氏胶的保护下穿过宫颈内腔,使其在分娩时极易破裂或自发膜破裂。这可能导致胎儿快速失血和死亡。虽然目前的治疗方法是在分娩前进行有计划的剖宫产,但最近出现了胎儿镜激光消融(FLA)作为一种微创替代方法,用于特定病例,特别是II型和III型前置血管,允许延长妊娠期和可能的阴道分娩。我们报告一例40岁妊娠3期妇女在22 + 5周时被诊断为II型前置血管。31 + 5周成功行FLA,无并发症。在36 + 5周时,她经历了自发的胎膜破裂,并应母亲的要求通过剖宫产产下了一名健康的男婴。为了将本病例置于背景中,我们对文献中的54例病例进行了系统回顾。FLA与98.1%的技术成功率、50%的阴道分娩率和100%的新生儿存活率相关,无重大产妇并发症报道。这些研究结果表明,FLA可能为特定患者提供一种安全有效的替代早产剖宫产的方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Prenatal Diagnosis
Prenatal Diagnosis 医学-妇产科学
CiteScore
5.80
自引率
13.30%
发文量
204
审稿时长
2 months
期刊介绍: Prenatal Diagnosis welcomes submissions in all aspects of prenatal diagnosis with a particular focus on areas in which molecular biology and genetics interface with prenatal care and therapy, encompassing: all aspects of fetal imaging, including sonography and magnetic resonance imaging; prenatal cytogenetics, including molecular studies and array CGH; prenatal screening studies; fetal cells and cell-free nucleic acids in maternal blood and other fluids; preimplantation genetic diagnosis (PGD); prenatal diagnosis of single gene disorders, including metabolic disorders; fetal therapy; fetal and placental development and pathology; development and evaluation of laboratory services for prenatal diagnosis; psychosocial, legal, ethical and economic aspects of prenatal diagnosis; prenatal genetic counseling
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