{"title":"Efficacy of lateral retinacular release versus no release in total knee arthroplasty: a systematic review and meta-analysis.","authors":"Yue Zou, Cuiqin Cao, Xiujiang Sun, Guodong Zhang","doi":"10.1186/s40001-025-03201-2","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the efficacy and safety of lateral patellar retinacular release (LPRR) versus no release in total knee arthroplasty (TKA).</p><p><strong>Methods: </strong>This PRISMA-compliant systematic review searched PubMed, Embase, Web of Science, Cochrane Library, CNKI, CBM, Wanfang, and VIP from inception to August 2024. We included comparative studies of TKA patients with vs without LPRR (n = 8 studies, 3,911 patients).</p><p><strong>Exclusion criteria: </strong>incomplete data, combined procedures, cadaveric/artificial models. Random-effects models analyzed outcomes; heterogeneity assessed via I<sup>2</sup> statistics.</p><p><strong>Results: </strong>Primary outcomes: LPRR significantly reduced anterior knee pain (OR = 0.23, 95% CI 0.13-0.42, P < 0.00001; I<sup>2</sup> = 0%) and improved Knee Society Score (KSS) (MD = 3.00, 95% CI 1.10-4.89, P = 0.002; I<sup>2</sup> = 0%) but increased infection rate (OR = 3.44, 95%CI 1.48-8.04, P = 0.004; I<sup>2</sup> = 26%). Secondary outcomes showed no significant differences (P > 0.05).</p><p><strong>Conclusion: </strong>LPRR reduces anterior knee pain but significantly increases infection risk (NNH = 32). Should be reserved for patients with intraoperative patellar maltracking after risk-benefit assessment. Findings are limited by predominant Asian cohorts, short follow-up durations, and heterogeneous surgical indications.</p>","PeriodicalId":11949,"journal":{"name":"European Journal of Medical Research","volume":"30 1","pages":"911"},"PeriodicalIF":3.4000,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12481734/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Medical Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s40001-025-03201-2","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: To evaluate the efficacy and safety of lateral patellar retinacular release (LPRR) versus no release in total knee arthroplasty (TKA).
Methods: This PRISMA-compliant systematic review searched PubMed, Embase, Web of Science, Cochrane Library, CNKI, CBM, Wanfang, and VIP from inception to August 2024. We included comparative studies of TKA patients with vs without LPRR (n = 8 studies, 3,911 patients).
Results: Primary outcomes: LPRR significantly reduced anterior knee pain (OR = 0.23, 95% CI 0.13-0.42, P < 0.00001; I2 = 0%) and improved Knee Society Score (KSS) (MD = 3.00, 95% CI 1.10-4.89, P = 0.002; I2 = 0%) but increased infection rate (OR = 3.44, 95%CI 1.48-8.04, P = 0.004; I2 = 26%). Secondary outcomes showed no significant differences (P > 0.05).
Conclusion: LPRR reduces anterior knee pain but significantly increases infection risk (NNH = 32). Should be reserved for patients with intraoperative patellar maltracking after risk-benefit assessment. Findings are limited by predominant Asian cohorts, short follow-up durations, and heterogeneous surgical indications.
期刊介绍:
European Journal of Medical Research publishes translational and clinical research of international interest across all medical disciplines, enabling clinicians and other researchers to learn about developments and innovations within these disciplines and across the boundaries between disciplines. The journal publishes high quality research and reviews and aims to ensure that the results of all well-conducted research are published, regardless of their outcome.