Jin Hui Ma, Hong Lin Zhang, En Ji Cui, Chang Ji Zheng
{"title":"A Novel Glycoside Compound and Antibacterial Constituents of the Fruits of Aronia melanocarpa","authors":"Jin Hui Ma, Hong Lin Zhang, En Ji Cui, Chang Ji Zheng","doi":"10.1007/s10600-025-04786-0","DOIUrl":null,"url":null,"abstract":"<p>A novel glycoside compound, 3-hydroxy-5-(<i>β</i>-D-glucopyranosyloxy)-hexanoic acid (<b>1</b>) has been isolated from the fruits of <i>Aronia melanocarpa</i> (Michx.) Britton, along with ten known compounds, vanillic acid 4-<i>O</i>-<i>β</i>-D-glucoside (<b>2</b>), (<i>R</i>)-4-<i>O-β</i>-D-glucopyranoyl-4-hydroxy-2-pentanone (<b>3</b>), (6<i>R</i>,9<i>R</i>)-roseoside (<b>4</b>), phloroacetophenone 2-<i>O</i>-glucoside (<b>5</b>), methyl (3<i>S,</i>5<i>S</i>)-5-hydroxy-3-(<i>β</i>-D-glucopyranosyloxy)hexanoate (<b>6</b>), <i>β</i>-D-glucopyranosyl benzoate (<b>7</b>), parasorboside (<b>8</b>), benzyl 6-<i>O-α</i>-L-arabinofuranosyl-<i>β</i>-D-glucoside (<b>9</b>), dihydrophasmaric acid 4′-<i>O-β</i>-D-glucopyranoside (<b>10</b>), and 4-<i>O-β</i>-D-glucopyranosyl-<i>cis-p</i>-coumaric acid (<b>11</b>). The structure of compound <b>1</b> was determined by NMR spectroscopic and MS analyses. Compounds <b>1–4</b> showed antibacterial activity against <i>Staphylococcus aureus</i> RN (4220).</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 5","pages":"916 - 920"},"PeriodicalIF":0.9000,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemistry of Natural Compounds","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s10600-025-04786-0","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}
引用次数: 0
Abstract
A novel glycoside compound, 3-hydroxy-5-(β-D-glucopyranosyloxy)-hexanoic acid (1) has been isolated from the fruits of Aronia melanocarpa (Michx.) Britton, along with ten known compounds, vanillic acid 4-O-β-D-glucoside (2), (R)-4-O-β-D-glucopyranoyl-4-hydroxy-2-pentanone (3), (6R,9R)-roseoside (4), phloroacetophenone 2-O-glucoside (5), methyl (3S,5S)-5-hydroxy-3-(β-D-glucopyranosyloxy)hexanoate (6), β-D-glucopyranosyl benzoate (7), parasorboside (8), benzyl 6-O-α-L-arabinofuranosyl-β-D-glucoside (9), dihydrophasmaric acid 4′-O-β-D-glucopyranoside (10), and 4-O-β-D-glucopyranosyl-cis-p-coumaric acid (11). The structure of compound 1 was determined by NMR spectroscopic and MS analyses. Compounds 1–4 showed antibacterial activity against Staphylococcus aureus RN (4220).
期刊介绍:
Chemistry of Natural Compounds publishes reviews and general articles about the structure of different classes of natural compounds, the chemical characteristics of botanical families, genus, and species, to establish the comparative laws and connection between physiological activity and the structure of substances.