A pillar[5]arene-based polydopamine-prodrug nanoplatform for targeted and synergistic chemodynamic-photothermalchemotherapy of cancer

IF 4.2 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemical Communications Pub Date : 2025-09-30 DOI:10.1039/d5cc05197e

Liang Li, Fuqiang Zhao, Xufeng Liang, Chunlin Deng, Jianxia Zhang, Tingting Chen, Yang Wang, Jin Wang, Yan Cai, Yong Yao

引用次数: 0

Abstract

A targeted nanoplatform was developed by formulating a polydopamine–prodrug conjugate with pillar[5]arene (P5PDA/DOX/Fe-Fa-Py), achieving potent antitumor activity through a targeted and synergistic combination of chemodynamic, photothermal, and chemotherapy.

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基于柱状[5]芳烃的聚多巴胺-前药纳米平台，用于靶向和协同化学动力学-光热化疗癌症

通过与柱状[5]芳烃（P5PDA/DOX/Fe-Fa-Py）组成聚多巴胺-前药偶联物，开发了靶向纳米平台，通过化学动力学、光热和化疗的靶向和协同组合，实现了有效的抗肿瘤活性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Chemical Communications 化学-化学综合

CiteScore

8.60

自引率

4.10%

发文量

2705

审稿时长

1.4 months

期刊介绍： ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.