Sulfonium Salt-Mediated Phosphorodithioation of Alkynes with P4S10 and Alcohols to Access Z-Vinyl Phosphorodithioates

Abstract

In this work, we report a practical and convenient sulfonium salt-mediated alkyne difunctionalization reaction. This method uses inexpensive P4S10 as both sulfur and phosphorus sources, providing an efficient approach for the access to various Z-vinyl phosphorodithioates. Preliminary studies suggest that the reaction undergoes a nucleophilic addition to in-situ generated alkynyl sulfonium salts and subsequently demethylation process.