{"title":"Analysis of clinical characteristics of multifocal electroretinogram and microperimetry in patients with high myopia","authors":"Xiaofan Yin , Peiyan Shi , Jinling Ge","doi":"10.1016/j.pdpdt.2025.105237","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>To investigate the role of microperimetry (MP) and multifocal electroretinogram (mfERG) in evaluating macular function in high myopia</div></div><div><h3>Methods</h3><div>From January to June 2025, data from 42 patients (76 eyes) undergoing both MP and mfERG at Jinan Mingshui Eye Hospital were retrospectively analyzed. The impact of axial length, atrophic macular degeneration (Atrophic, Tractional, Neovascular, ATN) grade, and age on the results was compared</div></div><div><h3>Results</h3><div>MP and mfERG results in pathological myopia were significantly lower than the normal range. Significant differences in light sensitivity and best-corrected visual acuity (BCVA) were found across different axial lengths, ATN grades, and age groups (<em>P</em> < 0.05). For amplitude density, Ring3 and Ring4 showed significant differences among axial lengths (<em>P</em> < 0.05), while Rings 1–5 exhibited significant differences among ATN grades and age groups (<em>P</em> < 0.05). Further clarification is needed for latency differences among these variables</div></div><div><h3>Conclusion</h3><div>MP and mfERG are valuable tools for assessing macular function changes in high myopia.</div></div>","PeriodicalId":20141,"journal":{"name":"Photodiagnosis and Photodynamic Therapy","volume":"56 ","pages":"Article 105237"},"PeriodicalIF":2.6000,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Photodiagnosis and Photodynamic Therapy","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1572100025007689","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Objective
To investigate the role of microperimetry (MP) and multifocal electroretinogram (mfERG) in evaluating macular function in high myopia
Methods
From January to June 2025, data from 42 patients (76 eyes) undergoing both MP and mfERG at Jinan Mingshui Eye Hospital were retrospectively analyzed. The impact of axial length, atrophic macular degeneration (Atrophic, Tractional, Neovascular, ATN) grade, and age on the results was compared
Results
MP and mfERG results in pathological myopia were significantly lower than the normal range. Significant differences in light sensitivity and best-corrected visual acuity (BCVA) were found across different axial lengths, ATN grades, and age groups (P < 0.05). For amplitude density, Ring3 and Ring4 showed significant differences among axial lengths (P < 0.05), while Rings 1–5 exhibited significant differences among ATN grades and age groups (P < 0.05). Further clarification is needed for latency differences among these variables
Conclusion
MP and mfERG are valuable tools for assessing macular function changes in high myopia.
期刊介绍:
Photodiagnosis and Photodynamic Therapy is an international journal for the dissemination of scientific knowledge and clinical developments of Photodiagnosis and Photodynamic Therapy in all medical specialties. The journal publishes original articles, review articles, case presentations, "how-to-do-it" articles, Letters to the Editor, short communications and relevant images with short descriptions. All submitted material is subject to a strict peer-review process.