The essential oil chemical composition of aerial parts of a new chemotype of Scutellaria altissima growing wild in North Macedonia.

IF 1.6 3区化学 Q3 CHEMISTRY, APPLIED

Natural Product Research Pub Date : 2025-09-29 DOI:10.1080/14786419.2025.2566910

Natale Badalamenti, Antonella Porrello, Vincenzo Ilardi, Maurizio Bruno

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Abstract

The genus Scutellaria L. (Lamiaceae) has a very wide geographical distribution across all temperate regions. Due to the potential medicinal value of Scutellaria, especially as antifeedant and anti-cancer, a very large number of phytochemical and pharmacology investigations have been carried out. Scutellaria altissima L. is a perennial herbaceous plant native to East Central Europe to Caucasus. Chemical composition of the essential oil from the aerial parts of S. altissima (Sa), collected in North Macedonia, and investigated for the first time in this study, was evaluated by gas chromatography (GC-MS). Sa (yield 0.01%), was characterised by good amounts of phenylpropanoids phenylpropanoids (54.2%), with myristicin (47.8%) as the principal metabolites of the oil. Other abundant compounds were linalool (13.1%), apiol (6.4%), and 1-octen-3-ol (4.9%). The chemical profile of Sa was compared with the composition all other essential oils (EOs) of Scutellaria species showing some peculiar characteristics.

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北马其顿野生黄芩一个新化学型地上部挥发油的化学成分。

黄芩属（Lamiaceae）在所有温带地区都有非常广泛的地理分布。由于黄芩具有潜在的药用价值，特别是具有防饲和抗癌作用，人们对其进行了大量的植物化学和药理学研究。黄芩（Scutellaria altissima L.）是一种多年生草本植物，原产于东欧至高加索地区。采用气相色谱-质谱法测定了首次在马其顿北部采集的山茱萸（S. altissima, Sa）地上部分挥发油的化学成分。Sa（产率0.01%）的特点是含有大量的苯丙素（54.2%），肉豆蔻素（47.8%）是油的主要代谢产物。其他丰富的化合物有芳樟醇（13.1%）、蜂油（6.4%）和1-辛烯-3-醇（4.9%）。将其化学成分与黄芩属植物精油进行了比较，发现其具有独特的化学特征。

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来源期刊

Natural Product Research 化学-医药化学

CiteScore

5.10

自引率

9.10%

发文量

605

审稿时长

2.1 months

期刊介绍： The aim of Natural Product Research is to publish important contributions in the field of natural product chemistry. The journal covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds. The communications include coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussions of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, eg. fermentation chemistry, plant tissue culture investigations etc., are accepted into the journal. Natural Product Research issues will be subtitled either ""Part A - Synthesis and Structure"" or ""Part B - Bioactive Natural Products"". for details on this , see the forthcoming articles section. All manuscript submissions are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is single blind and submission is online via ScholarOne Manuscripts.