Redefining Precision: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Comparing Robotic-Assisted Versus Laparoscopic Surgery in Colorectal Cancer.
Marcílio de Oliveira Filho, Miguel Chaves Lenzi, Pedro Emanuel Carneiro de Lima, Marina Azevedo Amaral, Phillip Anderson Silva Avelino, Pedro Laguardia Almeida, Altair Pereira de Melo Neto, Dante L S Souza, Eurico Cleto Ribeiro de Campos
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引用次数: 0
Abstract
Minimally invasive approaches such as laparoscopic surgery (LS) and robotic-assisted surgery (RAS) have transformed colorectal cancer (CRC) management. This systematic review and meta-analysis evaluated nine randomized controlled trials encompassing 2,758 patients to compare RAS and LS regarding perioperative, oncological, and long-term outcomes. RAS showed longer operative time but yielded benefits such as reduced conversion rates, greater lymph node retrieval, and lower circumferential resection margin (CRM) positivity. Both techniques demonstrated comparable safety, mortality, and overall complication rates. While RAS presents certain advantages, further research is required to determine its cost-effectiveness and long-term oncological impact. Trial Registration: PROSPERO CRD420251025102.
期刊介绍:
The Journal of Surgical Oncology offers peer-reviewed, original papers in the field of surgical oncology and broadly related surgical sciences, including reports on experimental and laboratory studies. As an international journal, the editors encourage participation from leading surgeons around the world. The JSO is the representative journal for the World Federation of Surgical Oncology Societies. Publishing 16 issues in 2 volumes each year, the journal accepts Research Articles, in-depth Reviews of timely interest, Letters to the Editor, and invited Editorials. Guest Editors from the JSO Editorial Board oversee multiple special Seminars issues each year. These Seminars include multifaceted Reviews on a particular topic or current issue in surgical oncology, which are invited from experts in the field.