M Laboissiere, I C S Araújo, N A Gomes, M B Café, N S M Leandro, E Arnhold, H van den Brand, M A Andrade, E Gonzales, J H Stringhini
{"title":"Effects of <i>in ovo</i> injection of 25(OH)D<sub>3</sub> in combination with Marek's disease vaccine on hatchability, performance and bone health of broilers.","authors":"M Laboissiere, I C S Araújo, N A Gomes, M B Café, N S M Leandro, E Arnhold, H van den Brand, M A Andrade, E Gonzales, J H Stringhini","doi":"10.1080/00071668.2025.2558996","DOIUrl":null,"url":null,"abstract":"<p><p>1. This study assessed the effects of <i>in ovo</i> injection of Marek's disease vaccine (MDV), alone (control) or combined with 1.25 μg of 25-hydroxycholecalciferol (25(OH)D<sub>3</sub>), on hatchability, chick quality, performance and bone quality in Cobb 500 broilers. At d 19 of embryo development, eggs were injected with 0.05 ml of MDV or MDV plus 1.25 μg of 25(OH)D<sub>3</sub> into the amniotic fluid following hatchery protocol. Post-hatch, 840, one-day-old male chicks were reared until d 35 of age.2. Hatchability and general chick quality were not affected by the treatments. However, the male chicks that received MDV + 1.25 μg of 25(OH)D<sub>3</sub> presented longer length at flock thinning compared to those that received only MDV. At 35 d of age, broiler performance, gait score and leg deformities (valgus and varus) were not affected.3. Although chicks receiving the MDV + 1.25 μg of 25(OH)D<sub>3</sub> had lower macroscopic tibial dyschondroplasia (TD) scores at 7 d of age compared to those given MDV, this difference was not sustained as they matured. Tibia weight, thickness and length were similar across treatments at all time points. However, the tibiae from chicks in the MDV + 1.25 μg 25(OH)D<sub>3</sub> group demonstrated greater strength on d 1 and 7 but not at later times.4. In conclusion, this study showed that combining 25(OH)D<sub>3</sub> with MDV does not impact hatchability or overall performance but does enhance early bone strength and growth in broiler chicks.</p>","PeriodicalId":9322,"journal":{"name":"British Poultry Science","volume":" ","pages":"1-8"},"PeriodicalIF":1.7000,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"British Poultry Science","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1080/00071668.2025.2558996","RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"AGRICULTURE, DAIRY & ANIMAL SCIENCE","Score":null,"Total":0}
引用次数: 0
Abstract
1. This study assessed the effects of in ovo injection of Marek's disease vaccine (MDV), alone (control) or combined with 1.25 μg of 25-hydroxycholecalciferol (25(OH)D3), on hatchability, chick quality, performance and bone quality in Cobb 500 broilers. At d 19 of embryo development, eggs were injected with 0.05 ml of MDV or MDV plus 1.25 μg of 25(OH)D3 into the amniotic fluid following hatchery protocol. Post-hatch, 840, one-day-old male chicks were reared until d 35 of age.2. Hatchability and general chick quality were not affected by the treatments. However, the male chicks that received MDV + 1.25 μg of 25(OH)D3 presented longer length at flock thinning compared to those that received only MDV. At 35 d of age, broiler performance, gait score and leg deformities (valgus and varus) were not affected.3. Although chicks receiving the MDV + 1.25 μg of 25(OH)D3 had lower macroscopic tibial dyschondroplasia (TD) scores at 7 d of age compared to those given MDV, this difference was not sustained as they matured. Tibia weight, thickness and length were similar across treatments at all time points. However, the tibiae from chicks in the MDV + 1.25 μg 25(OH)D3 group demonstrated greater strength on d 1 and 7 but not at later times.4. In conclusion, this study showed that combining 25(OH)D3 with MDV does not impact hatchability or overall performance but does enhance early bone strength and growth in broiler chicks.
期刊介绍:
From its first volume in 1960, British Poultry Science has been a leading international journal for poultry scientists and advisers to the poultry industry throughout the world. Over 60% of the independently refereed papers published originate outside the UK. Most typically they report the results of biological studies with an experimental approach which either make an original contribution to fundamental science or are of obvious application to the industry. Subjects which are covered include: anatomy, embryology, biochemistry, biophysics, physiology, reproduction and genetics, behaviour, microbiology, endocrinology, nutrition, environmental science, food science, feeding stuffs and feeding, management and housing welfare, breeding, hatching, poultry meat and egg yields and quality.Papers that adopt a modelling approach or describe the scientific background to new equipment or apparatus directly relevant to the industry are also published. The journal also features rapid publication of Short Communications. Summaries of papers presented at the Spring Meeting of the UK Branch of the WPSA are published in British Poultry Abstracts .