Research Advances of the Effects of Food and Medicine Homology Substances on Gastric Cancer

IF 3.1 2区医学 Q2 ONCOLOGY

Cancer Medicine Pub Date : 2025-09-29 DOI:10.1002/cam4.71242

Zhengyang Hao, Xiangjun Chen, Wenqian Tang, Ruipeng Wu, Bei Xue, Jingzhe Chen, Yidan Zhang, Shaokang Wang

{"title":"Research Advances of the Effects of Food and Medicine Homology Substances on Gastric Cancer","authors":"Zhengyang Hao, Xiangjun Chen, Wenqian Tang, Ruipeng Wu, Bei Xue, Jingzhe Chen, Yidan Zhang, Shaokang Wang","doi":"10.1002/cam4.71242","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>Gastric cancer (GC), a common malignant tumor, poses a significant threat to human health. Conventional radiotherapy and chemotherapy regimens come with significant drawbacks, including high toxicity, adverse side effects, inadequate targeting ability, and the potential for developing drug resistance, which ultimately diminishes patients' overall well-being.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>Food and medicine homology substances exhibit favorable pharmacological activity and minimal toxic side effects. They comprise a range of components that are beneficial to the human body, including high-quality proteins, vitamins, minerals, and other biologically active components such as polysaccharides, flavonoids, saponins, and alkaloids. In recent years, they have attracted considerable attention in the field of GC prevention and treatment. A comprehensive review of extant literature, alongside a rigorous analysis of contemporary nutrition and traditional Chinese medicine, forms the foundation of this study.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Its systematic approach encompasses the examination of the effects and mechanisms of food and medicine homology substances and their active ingredients on the prophylaxis and therapy of GC.</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>The study's findings expand the cognitive boundaries of GC prevention and improvement and offer novel insights and directions for the development of clinical anticancer therapeutic drugs.</p>\n </section>\n </div>","PeriodicalId":139,"journal":{"name":"Cancer Medicine","volume":"14 19","pages":""},"PeriodicalIF":3.1000,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12477795/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cancer Medicine","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/cam4.71242","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ONCOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Background

Gastric cancer (GC), a common malignant tumor, poses a significant threat to human health. Conventional radiotherapy and chemotherapy regimens come with significant drawbacks, including high toxicity, adverse side effects, inadequate targeting ability, and the potential for developing drug resistance, which ultimately diminishes patients' overall well-being.

Methods

Food and medicine homology substances exhibit favorable pharmacological activity and minimal toxic side effects. They comprise a range of components that are beneficial to the human body, including high-quality proteins, vitamins, minerals, and other biologically active components such as polysaccharides, flavonoids, saponins, and alkaloids. In recent years, they have attracted considerable attention in the field of GC prevention and treatment. A comprehensive review of extant literature, alongside a rigorous analysis of contemporary nutrition and traditional Chinese medicine, forms the foundation of this study.

Results

Its systematic approach encompasses the examination of the effects and mechanisms of food and medicine homology substances and their active ingredients on the prophylaxis and therapy of GC.

Conclusions

The study's findings expand the cognitive boundaries of GC prevention and improvement and offer novel insights and directions for the development of clinical anticancer therapeutic drugs.

Abstract Image

查看原文本刊更多论文

食品和药物同源物对胃癌作用的研究进展。

背景：胃癌是一种常见的恶性肿瘤，严重威胁着人类的健康。传统的放疗和化疗方案具有明显的缺点，包括高毒性、不良副作用、靶向能力不足以及产生耐药性的可能性，这最终会降低患者的整体健康状况。方法：食品和药品同源物质具有良好的药理活性和最小的毒副作用。它们含有一系列对人体有益的成分，包括高质量的蛋白质、维生素、矿物质和其他生物活性成分，如多糖、类黄酮、皂苷和生物碱。近年来，在胃癌防治领域引起了相当大的关注。对现有文献的全面回顾，以及对当代营养学和中医的严格分析，构成了本研究的基础。结果：系统地考察了食品和药品同源物质及其有效成分对胃癌的防治作用和机制。结论：本研究结果拓展了胃癌预防和改善的认知边界，为临床抗癌治疗药物的开发提供了新的见解和方向。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Cancer Medicine ONCOLOGY-

CiteScore

5.50

自引率

2.50%

发文量

907

审稿时长

19 weeks

期刊介绍： Cancer Medicine is a peer-reviewed, open access, interdisciplinary journal providing rapid publication of research from global biomedical researchers across the cancer sciences. The journal will consider submissions from all oncologic specialties, including, but not limited to, the following areas: Clinical Cancer Research Translational research ∙ clinical trials ∙ chemotherapy ∙ radiation therapy ∙ surgical therapy ∙ clinical observations ∙ clinical guidelines ∙ genetic consultation ∙ ethical considerations Cancer Biology: Molecular biology ∙ cellular biology ∙ molecular genetics ∙ genomics ∙ immunology ∙ epigenetics ∙ metabolic studies ∙ proteomics ∙ cytopathology ∙ carcinogenesis ∙ drug discovery and delivery. Cancer Prevention: Behavioral science ∙ psychosocial studies ∙ screening ∙ nutrition ∙ epidemiology and prevention ∙ community outreach. Bioinformatics: Gene expressions profiles ∙ gene regulation networks ∙ genome bioinformatics ∙ pathwayanalysis ∙ prognostic biomarkers. Cancer Medicine publishes original research articles, systematic reviews, meta-analyses, and research methods papers, along with invited editorials and commentaries. Original research papers must report well-conducted research with conclusions supported by the data presented in the paper.