Light-triggered quenching of the ¹⁹F-MRI signal from micelle-encapsulated PERFECTA.

IF 6.6 2区材料科学 Q1 CHEMISTRY, PHYSICAL

Nanoscale Horizons Pub Date : 2025-09-29 DOI:10.1039/d5nh00468c

Claire Leterrier, Guillaume Pinna, Marie Vandamme, Mélissa Glatigny, Erwan Selingue, Françoise Geffroy, Sébastien Mériaux, Edmond Gravel, Eric Doris

引用次数: 0

Abstract

We report the development of a fluorinated micellar nanosystem whose ¹⁹F-MRI signal can be selectively dimmed by application of an external stimulus. A photo-activatable quencher unit (ferrocene) was co-encapsulated with the superfluorinated PERFECTA probe in colloidal micelles. While pristine micelles were MRI responsive ("On" state), their irradiation by light triggered the "Off" MRI-state of PERFECTA.

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胶束封装PERFECTA的19F-MRI信号的光触发猝灭。

我们报道了一种氟化胶束纳米系统的发展，其19F-MRI信号可以通过外部刺激选择性地变暗。光活化猝灭单元（二茂铁）在胶体胶束中与超氟化PERFECTA探针共包被。虽然原始胶束是MRI响应（“开”状态），但它们的光照射触发了PERFECTA的“关”MRI状态。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nanoscale Horizons Materials Science-General Materials Science

CiteScore

16.30

自引率

1.00%

发文量

141

期刊介绍： Nanoscale Horizons stands out as a premier journal for publishing exceptionally high-quality and innovative nanoscience and nanotechnology. The emphasis lies on original research that introduces a new concept or a novel perspective (a conceptual advance), prioritizing this over reporting technological improvements. Nevertheless, outstanding articles showcasing truly groundbreaking developments, including record-breaking performance, may also find a place in the journal. Published work must be of substantial general interest to our broad and diverse readership across the nanoscience and nanotechnology community.

Light-triggered quenching of the 19F-MRI signal from micelle-encapsulated PERFECTA.

Abstract

Light-triggered quenching of the ¹⁹F-MRI signal from micelle-encapsulated PERFECTA.