Transoral Outlet Reduction for the Treatment of Dumping Syndrome After Roux-En-Y Gastric Bypass: A Systematic Review and Meta-Analysis.

IF 7.5 1区医学 Q1 GASTROENTEROLOGY & HEPATOLOGY

Gastrointestinal endoscopy Pub Date : 2025-09-25 DOI:10.1016/j.gie.2025.09.036

Douglas G Adler

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引用次数: 0

Abstract

Background and aims: Dumping syndrome (DS) is one of the significant limitations of the Roux-En-Y Gastric Bypass (RYGB) 's long-term success. Our study aimed to review the effectiveness and safety of transoral outlet reduction (TORe) for DS.

Methods: From inception to May 2024, an individualized search strategy for major databases was developed. The primary and secondary outcomes of our interest were TORe's technical and clinical success rates, peri-procedural adverse events, and reintervention rates.

Results: Four studies with 241 patients were included. The pooled technical success rate was 100% (CI: 99.08%-100%). The pooled mean Sigstad's score difference calculated before and after the procedure was 13.13 (CI: 11.90, 15.56, p < 0.01), reflecting clinical success. The pooled periprocedural adverse event rate was 10.46% (CI: 0.42%-28.30%), and the pooled reintervention rate was 7.99% (CI: 1.46%-18.05%).

Conclusion: Our study concludes that TORe is an effective and safe procedure for treating DS among RYGB patients.

查看原文本刊更多论文

经口出口复位治疗Roux-En-Y胃旁路术后倾倒综合征：系统回顾和荟萃分析。

背景与目的：倾倒综合征（DS）是Roux-En-Y胃旁路手术（RYGB）长期成功的重要限制之一。我们的研究旨在回顾经口出口复位（TORe）治疗退行性椎体滑移的有效性和安全性。方法：从成立到2024年5月，针对主要数据库制定个性化搜索策略。我们感兴趣的主要和次要结局是TORe的技术和临床成功率、术中不良事件和再干预率。结果：纳入4项研究，共241例患者。合并技术成功率为100% （CI: 99.08% ~ 100%）。手术前后Sigstad评分合计平均差值为13.13 (CI: 11.90, 15.56, p < 0.01)，反映临床成功。合并围手术期不良事件发生率为10.46% (CI: 0.42% ~ 28.30%)，合并再干预率为7.99% （CI: 1.46% ~ 18.05%）。结论：我们的研究表明，TORe是治疗RYGB患者退行性滑移的有效和安全的方法。

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来源期刊

Gastrointestinal endoscopy 医学-胃肠肝病学

CiteScore

10.30

自引率

7.80%

发文量

1441

审稿时长

38 days

期刊介绍： Gastrointestinal Endoscopy is a journal publishing original, peer-reviewed articles on endoscopic procedures for studying, diagnosing, and treating digestive diseases. It covers outcomes research, prospective studies, and controlled trials of new endoscopic instruments and treatment methods. The online features include full-text articles, video and audio clips, and MEDLINE links. The journal serves as an international forum for the latest developments in the specialty, offering challenging reports from authorities worldwide. It also publishes abstracts of significant articles from other clinical publications, accompanied by expert commentaries.