Collagen-Anchoring Polymer Dots Enable Rapid and Precise Detection of Microlesions in Inflammatory Bowel Disease through Perivascular Matrix Accumulation (Adv. Healthcare Mater. 25/2025)

IF 9.6 2区医学 Q1 ENGINEERING, BIOMEDICAL

Advanced Healthcare Materials Pub Date : 2025-09-29 DOI:10.1002/adhm.70237

Shuting Lu, Yuqiao Li, Zhuang Zhang, Minglei Teng, Jingwen Hou, Xi Tan, Qing Lu, Liqin Xiong

引用次数: 0

Abstract

Collagen-Anchoring Polymer Dots

Collagen-anchoring polymer dots (Pdots) selectively accumulate in the perivascular matrix of inflammatory bowel disease (IBD)-affected areas by leveraging pathological collagen upregulation. They enable rapid, high-contrast imaging of early microlesions and precise detection of subtle lesions, offering a breakthrough approach for early IBD diagnosis. More details can be found in the Research Article by Qing Lu, Liqin Xiong, and co-workers (DOI: 10.1002/adhm.202501580).

Abstract Image

查看原文本刊更多论文

胶原锚定聚合物点通过血管周围基质积累实现炎症性肠病微病变的快速精确检测（Adv. Healthcare Mater. 25/2025）

胶原-锚定聚合物点胶原-锚定聚合物点（Pdots）通过利用病理性胶原上调，选择性地积聚在炎症性肠病（IBD）患处的血管周围基质中。它们能够快速、高对比度地成像早期微病变，并精确检测细微病变，为早期IBD诊断提供了一种突破性的方法。更多细节可以在Lu Qing， Liqin Xiong及其同事的研究文章（DOI: 10.1002/ admm .202501580）中找到。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Advanced Healthcare Materials 工程技术-生物材料

CiteScore

14.40

自引率

3.00%

发文量

600

审稿时长

1.8 months

期刊介绍： Advanced Healthcare Materials, a distinguished member of the esteemed Advanced portfolio, has been dedicated to disseminating cutting-edge research on materials, devices, and technologies for enhancing human well-being for over ten years. As a comprehensive journal, it encompasses a wide range of disciplines such as biomaterials, biointerfaces, nanomedicine and nanotechnology, tissue engineering, and regenerative medicine.