ICU admission delays: Impact on length of stay and long-term outcomes.

0 MEDICINE, RESEARCH & EXPERIMENTAL
Ferhan Demirer Aydemir, Ozge Kurtkulagi, Bisar Ergun, Vecihe Bayrak, Ozlem Oner, Bilgin Comert, Ali Necati Gokmen, Volkan Hanci
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Abstract

Delays in intensive care unit (ICU) admissions are prevalent in overcrowded hospitals and can adversely affect patient outcomes. However, the extent of this impact, particularly beyond short-term mortality, remains unclear. We hypothesized that ICU admission delays exceeding 6 hours after consultation would independently increase 90-day mortality and prolong ICU length of stay. We conducted a retrospective analysis of data from 273 adult patients admitted to the ICU of a tertiary university hospital between January and December 2019. Patients were stratified into two groups: early admission (≤6 hours) and delayed admission (>6 hours). Multivariate Cox regression was employed to identify independent predictors of mortality. Delayed ICU admission was observed in 72.8% of patients. Although delayed admission was not independently associated with increased mortality in the multivariate analysis (HR: 0.88; 95% CI: 0.61-1.27), it was significantly correlated with prolonged ICU length of stay and higher 90-day mortality in the univariate analysis (p = 0.039), with no significant difference in vasopressor-free days (p = 0.809). In our assessment of independent mortality predictors, we found that patients with higher APACHE-II and Charlson scores experienced longer delays in ICU transfer. Additionally, respiratory and circulatory failure at admission were independently associated with increased mortality (HR: 2.17; 95% CI: 1.51-3.12). While early ICU admission did not independently predict mortality, it was linked to extended ICU stays, an increased treatment burden, and adverse long-term outcomes. These findings underscore the necessity of refining triage processes and evaluating baseline patient severity when interpreting the impact of ICU admission timing on outcomes.

ICU住院延误:对住院时间和长期预后的影响。
在人满为患的医院中,重症监护病房(ICU)入院的延误很普遍,并可能对患者的预后产生不利影响。然而,这种影响的程度,特别是短期死亡率以外的影响程度仍不清楚。我们假设会诊后超过6小时的ICU入院延迟会独立增加90天死亡率并延长ICU住院时间。我们对2019年1月至12月在某三级大学医院ICU住院的273名成年患者的数据进行了回顾性分析。患者分为早期入院(≤6小时)和延迟入院(≤6小时)两组。采用多变量Cox回归来确定死亡率的独立预测因素。延迟入住ICU的患者占72.8%。虽然在多变量分析中,延迟入院与死亡率增加没有独立相关(HR: 0.88; 95% CI: 0.61-1.27),但在单变量分析中,延迟入院与ICU住院时间延长和90天死亡率升高有显著相关(p = 0.039),无血管加压剂天数无显著差异(p = 0.809)。在我们对独立死亡率预测因素的评估中,我们发现APACHE-II和Charlson评分较高的患者在ICU转移时延迟更长。此外,入院时呼吸和循环衰竭与死亡率增加独立相关(HR: 2.17; 95% CI: 1.51-3.12)。虽然早期ICU入院并不能独立预测死亡率,但它与延长ICU住院时间、增加治疗负担和不良的长期预后有关。这些发现强调了在解释ICU入院时间对结果的影响时,改进分诊流程和评估基线患者严重程度的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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