Hazard and determinants of dropout and rehospitalization in patients with obesity after residential rehabilitation.

IF 3.5 2区 医学 Q1 Medicine
Daniele Sola, Samuele Minari, Raffaella Sabatino, Davide Soranna, Elisa Prina, Stefania Mai, Silvia Martinelli, Roberta Vietti, Raffaella Radin, Alessandra Rimella, Antonella Zambon, Massimo Scacchi
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Abstract

Purpose: To identify clinical and sociodemographic factors that predict follow-up discontinuation and rehospitalisation after multidisciplinary residential rehabilitation for severe obesity, thereby defining high-risk patient profiles and guiding tailored retention strategies.

Methods: We retrospectively followed 1,851 adults with obesity discharged from a multidisciplinary residential programme between 2015 and 2018 (median BMI 42 kg m⁻²). Dropout, defined as more than twelve months without contact, was studied with discrete-time survival models; time to rehospitalisation was analysed with Cox regression.

Results: Within twelve months 1,513 patients (87%) discontinued follow-up. Each five-year increase in age lowered drop-out risk (HR 0.97, 95% CI 0.94-0.99, p = 0.004); diabetes had a similar protective effect (HR 0.89, 0.79-1.00, p = 0.0455). Rehospitalisation occurred in 591 patients (32%). Risk increased with age (5-years increment; HR = 1.05, 95% CI 1.01-1.09, p = 0.0191), baseline BMI (HR = 1.04, 95% CI 1.03-1.05, p < 0.0001), diabetes (HR = 1.22, 95% CI 1.02-1.30, p = 0.0306) and eating disorders (HR = 1.48, 95% CI 1.07-2.05, p = 0.0193).

Discussion: Maintaining the benefits of residential rehabilitation is important. In our cohort, 87% of patients dropped out of follow-up within one year and 32% were readmitted. Two distinct profiles emerged: younger and non-diabetic subjects were prone to dropout, while patients with higher BMI, diabetes, or eating disorders were at higher risk of rehospitalization. Early identification of these groups may suggest flexible, technology-assisted follow-up for working-age patients and integrated metabolic-psychiatric care for complex cases, safeguarding outcomes and optimizing resources.

肥胖患者住院康复后辍学和再住院的危险和决定因素。
目的:确定预测重度肥胖患者多学科住院康复后随访中断和再住院的临床和社会人口学因素,从而确定高危患者概况并指导量身定制的保留策略。方法:我们回顾性地追踪了2015年至2018年期间从多学科住院项目出院的1851名肥胖成年人(中位数BMI为42 kg m⁻²)。用离散时间生存模型研究了辍学,定义为超过12个月没有接触;再住院时间采用Cox回归分析。结果:12个月内,1513例(87%)患者停止随访。年龄每增加5年,退出风险降低(HR 0.97, 95% CI 0.94-0.99, p = 0.004);糖尿病具有类似的保护作用(HR 0.89, 0.79-1.00, p = 0.0455)。591例患者(32%)再次住院。风险随年龄增加而增加(5岁增加;HR = 1.05, 95% CI 1.01-1.09, p = 0.0191),基线BMI (HR = 1.04, 95% CI 1.03-1.05, p)。在我们的队列中,87%的患者在一年内退出随访,32%的患者再次入院。两种不同的情况出现了:年轻和非糖尿病受试者容易退出,而BMI较高、糖尿病或饮食失调的患者再次住院的风险更高。早期识别这些群体可能建议对工作年龄患者进行灵活的、技术辅助的随访,并对复杂病例进行综合代谢-精神护理,以保障结果并优化资源。
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来源期刊
Journal of Endocrinological Investigation
Journal of Endocrinological Investigation ENDOCRINOLOGY & METABOLISM-
CiteScore
8.10
自引率
7.40%
发文量
242
期刊介绍: The Journal of Endocrinological Investigation is a well-established, e-only endocrine journal founded 36 years ago in 1978. It is the official journal of the Italian Society of Endocrinology (SIE), established in 1964. Other Italian societies in the endocrinology and metabolism field are affiliated to the journal: Italian Society of Andrology and Sexual Medicine, Italian Society of Obesity, Italian Society of Pediatric Endocrinology and Diabetology, Clinical Endocrinologists’ Association, Thyroid Association, Endocrine Surgical Units Association, Italian Society of Pharmacology.
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