Genomic Characteristics of a Novel Recombinant Bluetongue Virus Serotype 1 in Yunnan, China.

IF 2.3 2区 农林科学 Q2 VETERINARY SCIENCES
Yunyi Chen, Shimei Luo, Nijing Lei, Zhenghao Ye, Xianping Ma, Shaoyu Yang, Huaijie Jia, Guangyu Qi, Guanghua Wang, Huashan Yi
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引用次数: 0

Abstract

Bluetongue virus belongs to the Reoviridae family, which causes morbidity in ruminants. Herein, we report the full-length genome sequence of a recombinant BTV strain of serotype 1 (YNDH/103/2013) isolated from sentinel cattle in Yunnan Province, China, in 2013. To identify and understand the characteristics of YNDH/103/2013, we screened closely related viruses using Simplot 3.5.1 software and conducted verification via phylogenetic analysis using MEGA 11.0.13 software. Phylogenetic analysis and segment examination showed that the YNDH/103/2013 strain likely originated from multiple recombination events involving prevalent strains such as Y863, NRT37/ABT/HSR, and YTS-4 in China and India. The genome of BTV-1/YNDH/103/2013 derives from at least three reassortments with these strains, showing recombination breakpoints mainly in segments 4, 6, 8, and 9. This study improves our understanding of the origin and spread of BTV-1 in China.

云南省一种新型重组蓝舌病病毒血清1型的基因组特征
蓝舌病病毒属于呼肠孤病毒科,在反刍动物中引起发病。本文报道了2013年从中国云南省哨兵牛中分离到的血清型1重组BTV (YNDH/103/2013)的全基因组序列。为了鉴定和了解YNDH/103/2013病毒的特征,我们使用Simplot 3.5.1软件筛选密切相关的病毒,并使用MEGA 11.0.13软件进行系统发育分析验证。系统发育分析和片段检验显示,YNDH/103/2013菌株可能来源于中国和印度流行菌株Y863、NRT37/ABT/HSR和YTS-4的多次重组事件。BTV-1/YNDH/103/2013基因组与这些菌株至少有3次重组,重组断点主要在第4、6、8和9段。本研究提高了我们对BTV-1在中国的起源和传播的认识。
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来源期刊
Veterinary Sciences
Veterinary Sciences VETERINARY SCIENCES-
CiteScore
2.90
自引率
8.30%
发文量
612
审稿时长
6 weeks
期刊介绍: Veterinary Sciences is an international and interdisciplinary scholarly open access journal. It publishes original that are relevant to any field of veterinary sciences, including prevention, diagnosis and treatment of disease, disorder and injury in animals. This journal covers almost all topics related to animal health and veterinary medicine. Research fields of interest include but are not limited to: anaesthesiology anatomy bacteriology biochemistry cardiology dentistry dermatology embryology endocrinology epidemiology genetics histology immunology microbiology molecular biology mycology neurobiology oncology ophthalmology parasitology pathology pharmacology physiology radiology surgery theriogenology toxicology virology.
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