Demodex Mite Infestation in Patients Suffering from Atopic Dermatitis and Psoriasis.

IF 3.3 3区医学 Q2 MICROBIOLOGY

Pathogens Pub Date : 2025-09-22 DOI:10.3390/pathogens14090956

Agnieszka Borzęcka-Sapko, Magdalena Raszewska-Famielec, Aleksandra Sędzikowska, Alicja Buczek, Adam Wilmosz Borzęcki, Katarzyna Bartosik

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Abstract

The role of Demodex mites in the pathogenesis of skin diseases still needs updating. The aim of the study was to determine the relationship between Demodex sp. infestation and ocular and skin lesions in patients with atopic dermatitis (AD) and psoriasis (PsO). The control group comprised subjects that had not been diagnosed with any inflammatory skin disease. Direct microscopic examination (DME) was applied to analyze eyelashes and skin scraping samples. Demodex mites were detected more often in the eyelash samples than in the skin in both the AD (16.7% vs. 6.7%) and PsO (18.5% vs. 7.4%) patients as well as in the control group (25.8% vs. 3%). The mean intensity of Demodex infestation was 4.25 in the AD patients, 3.4 in the PsO patients, and 2.8 in the control group. Emollients were used in the treatment by 76.7% of the AD patients and 64.8% of patients with PsO; however, this type of skin care did not significantly increase the risk of skin colonization by Demodex. AD and PsO do not seem to facilitate excessive Demodex sp. proliferation. Nevertheless, diagnosis of the presence of these mites should be considered in patients with facial skin and ocular lesions that do not respond to the treatment.

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特应性皮炎和银屑病患者蠕形螨感染。

蠕形螨在皮肤病发病机制中的作用仍有待更新。本研究的目的是确定蠕形螨感染与特应性皮炎（AD）和牛皮癣（PsO）患者眼部和皮肤病变之间的关系。对照组由未被诊断患有任何炎症性皮肤病的受试者组成。采用直接显微检查（DME）对睫毛和皮肤刮拭样品进行分析。在AD患者（16.7% vs. 6.7%）和PsO患者（18.5% vs. 7.4%）以及对照组（25.8% vs. 3%）中，睫毛样本中检测到蠕形螨的频率高于皮肤样本中检测到的蠕形螨。AD组Demodex平均感染强度为4.25，PsO组为3.4，对照组为2.8。76.7%的AD患者和64.8%的PsO患者使用润肤剂治疗；然而，这种类型的皮肤护理并没有显著增加蠕形螨皮肤定植的风险。AD和PsO似乎不促进蠕形螨过度增殖。然而，在面部皮肤和眼部病变对治疗没有反应的患者中，应考虑诊断这些螨虫的存在。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pathogens Medicine-Immunology and Allergy

CiteScore

6.40

自引率

8.10%

发文量

1285

审稿时长

17.75 days

期刊介绍： Pathogens (ISSN 2076-0817) publishes reviews, regular research papers and short notes on all aspects of pathogens and pathogen-host interactions. There is no restriction on the length of the papers. Our aim is to encourage scientists to publish their experimental and theoretical research in as much detail as possible. Full experimental and/or methodical details must be provided for research articles.