Ecological and Regional Disparities in the Impact of Autoimmune Diseases on Global Labor Market Dynamics: A Cross-Sectional Study

IF 3.5 2区医学 Q1 MEDICINE, GENERAL & INTERNAL

Journal of Evidence‐Based Medicine Pub Date : 2025-09-26 DOI:10.1111/jebm.70073

Fen-Fen Li, Ke Han, Zi-Yue Fu, Bing-Yu Liang, Yan-Xun Han, Yu-Chen Liu, Ye-Hai Liu, Bu-Sheng Tong, Hai-Feng Pan

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引用次数: 0

Abstract

Aim

Climate change has intensified the prevalence of chronic diseases, particularly autoimmune diseases (ADs), which severely affect the health and labor market participation of the working-age population. While ADs are not typically fatal, their chronic nature and high disability rates lead to significant labor force attrition. This study explores the impact of ADs on the labor market, particularly in regions affected by climate change.

Methods

This study integrates labor market data with re-estimated ADs burden data from 1990 to 2021. Using time series analysis, multivariate regression, and geographic variation analysis, the research examines the relationship between ADs burden and labor force participation, with a focus on the exacerbating effects of climate change. Data was sourced from the International Labour Organization (ILO) and the Global Burden of Disease (GBD) database.

Results

In 2021, the global labor force with ADs was 86,295,350, with a prevalence rate of 1644.55 per 100,000. Women had a significantly higher prevalence (1841.96 per 100,000) compared to men (1448.6 per 100,000). The total disability-adjusted life Years (DALYs) for ADs was 18,513,645 person-years, with women experiencing higher DALYs (386.3 per 100,000). Regions severely affected by climate change showed increased ADs prevalence and a decline in labor force participation.

Conclusion

ADs significantly contribute to global labor market decline, with climate change amplifying the health burden. Gender disparities are notable, and ADs' impact on labor force participation highlights the need for comprehensive public health policies and labor market interventions.

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自身免疫性疾病对全球劳动力市场动态影响的生态和区域差异：一项横断面研究。

目的：气候变化加剧了慢性病，特别是自身免疫性疾病（ADs）的流行，严重影响了工作年龄人口的健康和劳动力市场参与。虽然ad通常不是致命的，但其慢性性质和高致残率导致了严重的劳动力流失。本研究探讨了农业发展对劳动力市场的影响，特别是在受气候变化影响的地区。方法：本研究将1990年至2021年的劳动力市场数据与重新估计的ad负担数据相结合。采用时间序列分析、多元回归分析和地理变异分析等方法，探讨了劳动参与率与ad负担之间的关系，并着重分析了气候变化的加剧效应。数据来自国际劳工组织（ILO）和全球疾病负担（GBD）数据库。结果：2021年，全球ad劳动力8629.5350人，患病率为1644.55 / 10万。女性的患病率（1841.96 / 10万）明显高于男性（1448.6 / 10万）。ad的总残疾调整生命年（DALYs）为18,513,645人年，女性经历更高的DALYs（386.3 / 100,000）。受气候变化影响严重的地区，ad患病率上升，劳动力参与率下降。结论：气候变化加剧了健康负担，ADs显著加剧了全球劳动力市场的衰退。性别差异是显著的，艾滋病对劳动力参与的影响突出表明需要制定全面的公共卫生政策和劳动力市场干预措施。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Evidence‐Based Medicine MEDICINE, GENERAL & INTERNAL-

CiteScore

11.20

自引率

1.40%

发文量

期刊介绍： The Journal of Evidence-Based Medicine (EMB) is an esteemed international healthcare and medical decision-making journal, dedicated to publishing groundbreaking research outcomes in evidence-based decision-making, research, practice, and education. Serving as the official English-language journal of the Cochrane China Centre and West China Hospital of Sichuan University, we eagerly welcome editorials, commentaries, and systematic reviews encompassing various topics such as clinical trials, policy, drug and patient safety, education, and knowledge translation.