Managing residual volumes in penile girth enhancement with hyaluronic acid fillers: a case series and literature review.

Abstract

Hyaluronic acid (HA) fillers are widely used in aesthetic medicine due to their biocompatibility and reversibility with hyaluronidase. However, their use in penile augmentation (PA) remains limited, and knowledge of hyaluronidase application in this context is sparse. This case series presents four patients with residual HA from previous penile girth enhancement (PGE), successfully managed using hyaluronidase. These cases illustrate its utility in correcting asymmetries, managing adverse effects, and preparing the site for reinjection. Although underutilized in urologic practice, hyaluronidase represents an effective adjunct in the refinement and maintenance of HA-based PGE.