{"title":"Clinics in Dermatology: Herpes Simplex (Update on dermatological aspects of STD and HIV)NEED SOME PICTURES.","authors":"Emily Clarke","doi":"10.1016/j.clindermatol.2025.09.010","DOIUrl":null,"url":null,"abstract":"<p><p>Herpes simplex virus (HSV) is the most common cause of anogenital ulceration worldwide. There are two distinct viruses: HSV-1 associated with oro-labial cold sores and genital infection, and HSV-2 associated with genital infection. Infection is lifelong, and typically presents with painful anogenital ulceration which may recur after periods of latency. Asymptomatic shedding is common and may lead to transmission to sexual partners. Antiviral suppression with aciclovir, valaciclovir or famciclovir is useful to treat initial painful episodes, or troublesome recurrent infection. Suppressive antiviral therapy, condoms, selective abstinence and disclosure to sexual partners have all been demonstrated to reduce the risk of transmission.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.2000,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinics in dermatology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.clindermatol.2025.09.010","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"DERMATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Herpes simplex virus (HSV) is the most common cause of anogenital ulceration worldwide. There are two distinct viruses: HSV-1 associated with oro-labial cold sores and genital infection, and HSV-2 associated with genital infection. Infection is lifelong, and typically presents with painful anogenital ulceration which may recur after periods of latency. Asymptomatic shedding is common and may lead to transmission to sexual partners. Antiviral suppression with aciclovir, valaciclovir or famciclovir is useful to treat initial painful episodes, or troublesome recurrent infection. Suppressive antiviral therapy, condoms, selective abstinence and disclosure to sexual partners have all been demonstrated to reduce the risk of transmission.
期刊介绍:
Clinics in Dermatology brings you the most practical and comprehensive information on the treatment and care of skin disorders. Each issue features a Guest Editor and is devoted to a single timely topic relating to clinical dermatology.
Clinics in Dermatology provides information that is...
• Clinically oriented -- from evaluation to treatment, Clinics in Dermatology covers what is most relevant to you in your practice.
• Authoritative -- world-renowned experts in the field assure the high-quality and currency of each issue by reporting on their areas of expertise.
• Well-illustrated -- each issue is complete with photos, drawings and diagrams to illustrate points and demonstrate techniques.