V. B. Rogozhin, A. A. Lezova, A. A. Lezov, N. V. Tsvetkov
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引用次数: 0
Abstract
The anomalous solubility of an interpolyelectrolyte complex (IPEC) of chitosan (CN) and sodium chondroitin sulfate (SCS) in a monosodium glutamate (MSG) solution associated with its dissociation into the initial components is discovered and studied using viscometry, turbidimetry, dynamic light scattering, static light scattering, and gravimetry. It is shown that complete dissociation of the stoichiometric interpolyelectrolyte complex of the said polyelectrolytes can be achieved in a monosodium glutamate solution with an order of magnitude lower ionic strength than in solutions of other salts. The possibility of the reverse formation of the interpolyelectrolyte complex of chitosan and sodium chondroitin sulfate from its decay products as the concentration of monosodium glutamate decreases is revealed. The possible areas of application of this phenomenon are identified, in particular, in medicine.
期刊介绍：
Nanobiotechnology Reports publishes interdisciplinary research articles on fundamental aspects of the structure and properties of nanoscale objects and nanomaterials, polymeric and bioorganic molecules, and supramolecular and biohybrid complexes, as well as articles that discuss technologies for their preparation and processing, and practical implementation of products, devices, and nature-like systems based on them. The journal publishes original articles and reviews that meet the highest scientific quality standards in the following areas of science and technology studies: self-organizing structures and nanoassemblies; nanostructures, including nanotubes; functional and structural nanomaterials; polymeric, bioorganic, and hybrid nanomaterials; devices and products based on nanomaterials and nanotechnology; nanobiology and genetics, and omics technologies; nanobiomedicine and nanopharmaceutics; nanoelectronics and neuromorphic computing systems; neurocognitive systems and technologies; nanophotonics; natural science methods in a study of cultural heritage items; metrology, standardization, and monitoring in nanotechnology.
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