{"title":"Patented technologies of microfluidic devices for targeted drug delivery: a revolution in optimization","authors":"Dilpreet Singh","doi":"10.1007/s10404-025-02814-7","DOIUrl":null,"url":null,"abstract":"<div><p>Microfluidic devices have emerged as transformative tools in the field of targeted drug delivery, offering unprecedented precision, efficiency, and control. Patented innovations in microfluidics focus on creating tailored delivery systems capable of overcoming biological barriers, optimizing therapeutic dosing, and minimizing systemic side effects. By integrating advanced materials, microfabrication techniques, and dynamic fluid control, these devices enable localized and sustained release of therapeutics. Applications span oncology, neurology, and chronic disease management, addressing challenges such as drug stability, biodistribution, and cellular targeting. This paper explores patented microfluidic technologies, emphasizing their design principles, functional mechanisms, and their role in revolutionizing drug delivery. Furthermore, we discuss the future prospects and commercialization potential of these devices as key enablers of personalized medicine.</p></div>","PeriodicalId":706,"journal":{"name":"Microfluidics and Nanofluidics","volume":"29 6","pages":""},"PeriodicalIF":2.5000,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Microfluidics and Nanofluidics","FirstCategoryId":"5","ListUrlMain":"https://link.springer.com/article/10.1007/s10404-025-02814-7","RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"INSTRUMENTS & INSTRUMENTATION","Score":null,"Total":0}
引用次数: 0
Abstract
Microfluidic devices have emerged as transformative tools in the field of targeted drug delivery, offering unprecedented precision, efficiency, and control. Patented innovations in microfluidics focus on creating tailored delivery systems capable of overcoming biological barriers, optimizing therapeutic dosing, and minimizing systemic side effects. By integrating advanced materials, microfabrication techniques, and dynamic fluid control, these devices enable localized and sustained release of therapeutics. Applications span oncology, neurology, and chronic disease management, addressing challenges such as drug stability, biodistribution, and cellular targeting. This paper explores patented microfluidic technologies, emphasizing their design principles, functional mechanisms, and their role in revolutionizing drug delivery. Furthermore, we discuss the future prospects and commercialization potential of these devices as key enablers of personalized medicine.
期刊介绍：
Microfluidics and Nanofluidics is an international peer-reviewed journal that aims to publish papers in all aspects of microfluidics, nanofluidics and lab-on-a-chip science and technology. The objectives of the journal are to (1) provide an overview of the current state of the research and development in microfluidics, nanofluidics and lab-on-a-chip devices, (2) improve the fundamental understanding of microfluidic and nanofluidic phenomena, and (3) discuss applications of microfluidics, nanofluidics and lab-on-a-chip devices. Topics covered in this journal include:
1.000 Fundamental principles of micro- and nanoscale phenomena like,
flow, mass transport and reactions
3.000 Theoretical models and numerical simulation with experimental and/or analytical proof
4.000 Novel measurement & characterization technologies
5.000 Devices (actuators and sensors)
6.000 New unit-operations for dedicated microfluidic platforms
7.000 Lab-on-a-Chip applications
8.000 Microfabrication technologies and materials
Please note, Microfluidics and Nanofluidics does not publish manuscripts studying pure microscale heat transfer since there are many journals that cover this field of research (Journal of Heat Transfer, Journal of Heat and Mass Transfer, Journal of Heat and Fluid Flow, etc.).
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