Advances in nanocomposite larvicides for mosquito vector management: a comprehensive review

IF 2.6 Q2 MULTIDISCIPLINARY SCIENCES
Kiruthiga Natarajan, Rajkuberan Chandrasekaran, Selvakumar Thirumalaisamy, Kalaiselvi Aasaithambi, John Joseph
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引用次数: 0

Abstract

Background

The occurrence of malaria, filariasis, yellow fever, West Nile virus, chikungunya, Zika, and dengue diseases causes significant morbidity and mortality in underdeveloped countries due to the emergence of virulent strains and the development of drug resistance. Nanotechnology, a potent tool, can mitigate the mosquito’s emergence and larvae breeding sources effectively. Nanocomposites, an amalgamation of metals/metal oxide/polymer, will target the specific mosquitoes and can suppress their growth and development. Therefore, our objective is to explore the larvicidal potency of nanocomposites in the larvae of Aedes aegypti, Culex quinquefasciatus, Anopheles stephensi, and Culex pipiens and to address the possible use of nanocomposites as insecticides in Integrated Pest Management.

Main body

Nanocomposites have diverse applications in biological sectors due to the distinctive optical and physical chemical properties. These tailored composites can tackle virulent strains, and mosquitoes can’t develop resistance. Nanocomposites act against larvae of various developmental stages (1st–4th instar) in Ae.aegypti, Cx. quinquefasciatus, An.stephensi, and Cx. pipiens with significant LC50 values. The larvicidal effect of the nanocomposite is influenced by species-specific, size and shape, surface coating, and others. The nanocomposites induce reactive oxygen species (ROS), triggering oxidative stress and activating apoptosis mechanisms in the larvae. From the available literature studies, nanocomposites are effective against Ae. aegypti > Cx. quinquefasciatus > Cx. pipiens > An. stephensi mosquitoes.

Conclusion

The nanocomposites are effective against all stages of mosquito larvae and can be further formulated as an insecticide to control the mosquito menace. Thus, the nanocomposites are a novel material for the eradication of juvenile mosquitoes with higher efficacy and efficiency.

用于蚊虫媒介管理的纳米复合杀幼虫剂研究进展综述
疟疾、丝虫病、黄热病、西尼罗河病毒、基孔肯雅热、寨卡病毒和登革热等疾病的发生,由于毒株的出现和耐药性的发展,在不发达国家造成了显著的发病率和死亡率。纳米技术是一种有效的工具,可以有效地减少蚊子的出现和幼虫的滋生来源。纳米复合材料是一种金属/金属氧化物/聚合物的混合物,将针对特定的蚊子,并可以抑制它们的生长和发育。因此,我们的目标是探索纳米复合材料对埃及伊蚊、致倦库蚊、斯氏按蚊和淡纹库蚊幼虫的杀幼虫效力,并探讨纳米复合材料在害虫综合治理中的应用可能性。纳米复合材料由于其独特的光学和物理化学性质,在生物领域有着广泛的应用。这些定制的复合材料可以对付有毒菌株,蚊子也不会产生抗药性。纳米复合材料对伊蚊不同发育阶段(1 ~ 4龄)幼虫均有一定的抑制作用。蚊,残雪。quinquefasciatus,。stephensi和Cx。LC50值显著的库蚊。纳米复合材料的杀虫效果受物种特异性、尺寸和形状、表面涂层等因素的影响。纳米复合材料诱导活性氧(ROS),引发氧化应激并激活幼虫的凋亡机制。从现有的文献研究来看,纳米复合材料对伊蚊有较好的抑制作用。埃及;埃及;quinquciciciatus;臭虫>;stephensi蚊子。结论该纳米复合材料对各阶段蚊虫幼虫均有较好的杀灭效果,可进一步配制成防蚊剂。因此,该纳米复合材料具有较高的灭蚊效果和效率,是一种新型的灭蚊材料。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
2.60
自引率
0.00%
发文量
0
期刊介绍: Beni-Suef University Journal of Basic and Applied Sciences (BJBAS) is a peer-reviewed, open-access journal. This journal welcomes submissions of original research, literature reviews, and editorials in its respected fields of fundamental science, applied science (with a particular focus on the fields of applied nanotechnology and biotechnology), medical sciences, pharmaceutical sciences, and engineering. The multidisciplinary aspects of the journal encourage global collaboration between researchers in multiple fields and provide cross-disciplinary dissemination of findings.
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