{"title":"Folic Acid Sensing using CdTe doped Polyvinyl Alcohol Nanocomposite Hydrogels","authors":"Baharul Islam, Rajashree Bortamuly, Samiul Hoque, Hirendra Das, Pranjal Saikia","doi":"10.1134/S1560090424600980","DOIUrl":null,"url":null,"abstract":"<p>In the present work, a comprehensive study is carried out to use amino acid mixed polyvinyl alcohol (PVA) based hybrid hydrogels as sensing material for detection of folic acid (FA). Thioglycolic acid (TGA) capped cadmium telluride (CdTe) nanostructures were used as dopant to enhance the efficiency and sensitivity of the PVA hydrogels. Three different types of hybrid hydrogels were synthesized using <i>L</i>-phenylalanine (PA), <i>L</i>-leucine (LEU) and <i>L-</i>tyrosine (TYR). Various chemical and physical characterizations were carried out to investigate the properties of TGA/CdTe nanostructures and PVA based hybrid hydrogels. A fluorescence quenching based detection technique was developed to detect the concentrations of FA. From the analysis of these six different hydrogels, it was observed that CdTe doped hybrid hydrogels show the best performance with sensitivity in the range of 0.229 µg/cm<sup>3</sup> with limit of detection of 1.86 ng/cm<sup>3</sup>.</p>","PeriodicalId":739,"journal":{"name":"Polymer Science, Series B","volume":"66 6","pages":"768 - 776"},"PeriodicalIF":1.0000,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Polymer Science, Series B","FirstCategoryId":"1","ListUrlMain":"https://link.springer.com/article/10.1134/S1560090424600980","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"POLYMER SCIENCE","Score":null,"Total":0}
引用次数: 0
Abstract
In the present work, a comprehensive study is carried out to use amino acid mixed polyvinyl alcohol (PVA) based hybrid hydrogels as sensing material for detection of folic acid (FA). Thioglycolic acid (TGA) capped cadmium telluride (CdTe) nanostructures were used as dopant to enhance the efficiency and sensitivity of the PVA hydrogels. Three different types of hybrid hydrogels were synthesized using L-phenylalanine (PA), L-leucine (LEU) and L-tyrosine (TYR). Various chemical and physical characterizations were carried out to investigate the properties of TGA/CdTe nanostructures and PVA based hybrid hydrogels. A fluorescence quenching based detection technique was developed to detect the concentrations of FA. From the analysis of these six different hydrogels, it was observed that CdTe doped hybrid hydrogels show the best performance with sensitivity in the range of 0.229 µg/cm3 with limit of detection of 1.86 ng/cm3.
期刊介绍:
Polymer Science, Series B is a journal published in collaboration with the Russian Academy of Sciences. Series B experimental and theoretical papers and reviews dealing with the synthesis, kinetics, catalysis, and chemical transformations of macromolecules, supramolecular structures, and polymer matrix-based composites (6 issues a year). All journal series present original papers and reviews covering all fundamental aspects of macromolecular science. Contributions should be of marked novelty and interest for a broad readership. Articles may be written in English or Russian regardless of country and nationality of authors. All manuscripts are peer reviewed