Gellan and Pullulan Hydrogels of Different Molar Mass

IF 0.8 Q3 Engineering
M. E. Mikhailova, A. V. Donets, V. B. Rogozhin, N. G. Mikusheva, A. A. Lezova, A. A. Lezov, N. V. Tsvetkov
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引用次数: 0

Abstract

A number of systems capable of forming gels upon contact with an aqueous solution of NaCl, two components of which are represented by gellan and CaCl2, are studied. The third component is pullulan with different molar masses. Systems such as these could be used for medical purposes, particularly for the delivery and controlled release of drugs. The influence of the molar mass of pullulan on the rheology of the resulting gel is analyzed to optimize its viscoelastic properties. It is that reducing the molar mass of pullulan integrated into the gel composition improves the viscoelastic properties of the system. It is established that the gels obtained at room temperature during interaction with an aqueous solution of NaCl did not deteriorate when heated up to temperatures of ~60–70°C.

Abstract Image

不同摩尔质量的结冷胶和普鲁兰水凝胶
研究了许多与氯化钠水溶液接触后能形成凝胶的体系,其中两种组分以结冷胶和CaCl2为代表。第三种成分是不同摩尔质量的普鲁兰。诸如此类的系统可用于医疗目的,特别是用于药物的输送和控制释放。分析了普鲁兰的摩尔质量对凝胶流变性能的影响,以优化其粘弹性性能。这是减少整合到凝胶组合物中的普鲁兰的摩尔质量改善了体系的粘弹性性能。在室温下与NaCl水溶液相互作用得到的凝胶在加热到~60 ~ 70℃时不会变质。
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来源期刊
Nanotechnologies in Russia
Nanotechnologies in Russia NANOSCIENCE & NANOTECHNOLOGY-
CiteScore
1.20
自引率
0.00%
发文量
0
期刊介绍: Nanobiotechnology Reports publishes interdisciplinary research articles on fundamental aspects of the structure and properties of nanoscale objects and nanomaterials, polymeric and bioorganic molecules, and supramolecular and biohybrid complexes, as well as articles that discuss technologies for their preparation and processing, and practical implementation of products, devices, and nature-like systems based on them. The journal publishes original articles and reviews that meet the highest scientific quality standards in the following areas of science and technology studies: self-organizing structures and nanoassemblies; nanostructures, including nanotubes; functional and structural nanomaterials; polymeric, bioorganic, and hybrid nanomaterials; devices and products based on nanomaterials and nanotechnology; nanobiology and genetics, and omics technologies; nanobiomedicine and nanopharmaceutics; nanoelectronics and neuromorphic computing systems; neurocognitive systems and technologies; nanophotonics; natural science methods in a study of cultural heritage items; metrology, standardization, and monitoring in nanotechnology.
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