A. A. Lezov, I. Yu. Perevyazko, A. A. Lezova, V. B. Rogozhin, N. G. Mikusheva, P. A. Fetin, A. S. Senchukova, M. E. Mikhailova, A. V. Donets, M. A. Vovk, I. M. Zorin, N. V. Tsvetkov
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引用次数: 0
Abstract
Grafted copolymers based on natural polysaccharides are interesting from the standpoint of creating targeted drug delivery systems. The properties of graft copolymers of pullulan with side chains of poly(2-methyl-2-oxazoline) and poly(2-ethyl-2-oxazoline) are studied. The conformational and hydrodynamic characteristics of the indicated polymers, such as the coefficient of translational diffusion, characteristic viscosity, molecular weight, equilibrium rigidity, and hydrodynamic diameter of chains, are determined using nuclear magnetic resonance, dynamic light scattering, analytical ultracentrifugation, viscometry, and a number of combined techniques. Increase of the value of equilibrium rigidity of grafted polymers with poly(2-oxazoline) side chains was detected.
期刊介绍:
Nanobiotechnology Reports publishes interdisciplinary research articles on fundamental aspects of the structure and properties of nanoscale objects and nanomaterials, polymeric and bioorganic molecules, and supramolecular and biohybrid complexes, as well as articles that discuss technologies for their preparation and processing, and practical implementation of products, devices, and nature-like systems based on them. The journal publishes original articles and reviews that meet the highest scientific quality standards in the following areas of science and technology studies: self-organizing structures and nanoassemblies; nanostructures, including nanotubes; functional and structural nanomaterials; polymeric, bioorganic, and hybrid nanomaterials; devices and products based on nanomaterials and nanotechnology; nanobiology and genetics, and omics technologies; nanobiomedicine and nanopharmaceutics; nanoelectronics and neuromorphic computing systems; neurocognitive systems and technologies; nanophotonics; natural science methods in a study of cultural heritage items; metrology, standardization, and monitoring in nanotechnology.