Effects of PHB and PLA coatings on the corrosion behavior of ultrathin Mg sheets in artificial blood plasma containing BSA

IF 11 1区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

Rare Metals Pub Date : 2025-06-24 DOI:10.1007/s12598-025-03387-8

Bi-Wei Sun, Ju-Yi Yang, Jian-Wei Dai, Yan-Bin Zhao, Lu Zhang, Zi-Jian Huang, Jing Bai, Feng Xue, Paul K. Chu, Cheng-Lin Chu

{"title":"Effects of PHB and PLA coatings on the corrosion behavior of ultrathin Mg sheets in artificial blood plasma containing BSA","authors":"Bi-Wei Sun, Ju-Yi Yang, Jian-Wei Dai, Yan-Bin Zhao, Lu Zhang, Zi-Jian Huang, Jing Bai, Feng Xue, Paul K. Chu, Cheng-Lin Chu","doi":"10.1007/s12598-025-03387-8","DOIUrl":null,"url":null,"abstract":"<div><p>Biodegradable polymer coatings are commonly used as protective barriers on magnesium (Mg) and its alloys. The properties of polymers, such as crystallinity and degradation properties, have a crucial impact on their corrosion resistance. In this work, polyhydroxybutyrate (PHB) coatings are deposited on Mg sheets with a thickness similar to that of cardiovascular stents to assess the degradation behavior, and poly-lactic acid (PLA)-coated Mg is also investigated to compare the structure–property-performance relationship. The hydrogen evolution volume (HEV) of the PHB-coated sample decreases by 30% after immersion in artificial blood plasma (AP) for 7 days, whereas the PLA-coated sample shows an increase of 154%. The PHB coating also shows excellent durability at a constant voltage, compared to severe rupture of the PLA coating. The degradation behavior of the coated-Mg samples is evaluated in AP solution containing different concentrations of the bovine serum albumin (BSA). Corrosion is inhibited as the protein concentration increases. The degradation rates of the Mg, PLA-coated Mg, and PHB-coated Mg decrease by 65%, 88%, and 75% for 5 g L<sup>−1</sup> BSA, respectively. Our results reveal that higher crystallinity and less acidic degradation products give rise to better durability, while the acid self-catalytic effect leads to the failure of PLA. The protein-polymer interactions are determined and the empirical relationship of HEV is established.</p><h3>Graphical Abstract</h3>\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":749,"journal":{"name":"Rare Metals","volume":"44 8","pages":"5656 - 5671"},"PeriodicalIF":11.0000,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Rare Metals","FirstCategoryId":"88","ListUrlMain":"https://link.springer.com/article/10.1007/s12598-025-03387-8","RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

Abstract

Biodegradable polymer coatings are commonly used as protective barriers on magnesium (Mg) and its alloys. The properties of polymers, such as crystallinity and degradation properties, have a crucial impact on their corrosion resistance. In this work, polyhydroxybutyrate (PHB) coatings are deposited on Mg sheets with a thickness similar to that of cardiovascular stents to assess the degradation behavior, and poly-lactic acid (PLA)-coated Mg is also investigated to compare the structure–property-performance relationship. The hydrogen evolution volume (HEV) of the PHB-coated sample decreases by 30% after immersion in artificial blood plasma (AP) for 7 days, whereas the PLA-coated sample shows an increase of 154%. The PHB coating also shows excellent durability at a constant voltage, compared to severe rupture of the PLA coating. The degradation behavior of the coated-Mg samples is evaluated in AP solution containing different concentrations of the bovine serum albumin (BSA). Corrosion is inhibited as the protein concentration increases. The degradation rates of the Mg, PLA-coated Mg, and PHB-coated Mg decrease by 65%, 88%, and 75% for 5 g L⁻¹ BSA, respectively. Our results reveal that higher crystallinity and less acidic degradation products give rise to better durability, while the acid self-catalytic effect leads to the failure of PLA. The protein-polymer interactions are determined and the empirical relationship of HEV is established.

Graphical Abstract

查看原文本刊更多论文

PHB和PLA涂层对超薄Mg片在含BSA人工血浆中腐蚀行为的影响

生物可降解聚合物涂层通常用作镁及其合金的保护屏障。聚合物的结晶度和降解性等性能对其耐腐蚀性有至关重要的影响。在这项工作中，聚羟基丁酸盐（PHB）涂层沉积在与心血管支架厚度相似的Mg片上，以评估降解行为，并研究聚乳酸（PLA）涂层Mg，以比较结构-性能-性能关系。在人工血浆（AP）中浸泡7天后，phb包被样品的析氢体积（HEV）降低了30%，而pla包被样品的析氢体积（HEV）增加了154%。与PLA涂层的严重破裂相比，PHB涂层在恒定电压下也表现出优异的耐久性。在含有不同浓度牛血清白蛋白（BSA）的AP溶液中，评价了包覆mg样品的降解行为。随着蛋白质浓度的增加，腐蚀被抑制。Mg、pla包覆Mg和phb包覆Mg对5 g L−1 BSA的降解率分别降低了65%、88%和75%。研究结果表明，较高的结晶度和较少的酸性降解产物可以提高PLA的耐久性，而酸性自催化效应导致PLA失效。测定了蛋白质与聚合物的相互作用，建立了HEV的经验关系。图形抽象

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Rare Metals 工程技术-材料科学：综合

CiteScore

12.10

自引率

12.50%

发文量

2919

审稿时长

2.7 months

期刊介绍： Rare Metals is a monthly peer-reviewed journal published by the Nonferrous Metals Society of China. It serves as a platform for engineers and scientists to communicate and disseminate original research articles in the field of rare metals. The journal focuses on a wide range of topics including metallurgy, processing, and determination of rare metals. Additionally, it showcases the application of rare metals in advanced materials such as superconductors, semiconductors, composites, and ceramics.