Tuning the Magnetoelectric Stimulation Method to Enhance Cell Proliferation in PVDF-based Nanocomposites

IF 0.8 Q3 Engineering

Nanotechnologies in Russia Pub Date : 2025-07-21 DOI:10.1134/S2635167624602559

V. Salnikov, V. Antipova, P. Vorontsov, D. Turusheva, A. Ignatov, P. Ershov, K. Levada, A. Omelyanchik, V. Rodionova

引用次数: 0

Abstract

A combination of materials such as a PVDF-based composite with 10 wt % CoFe₂O₄ nanoparticles and a method of ME stimulation of stem cells using a perpendicularly shifting low-frequency (0.3 Hz) magnetic field with a given amplitude are proposed. Optimal stimulation parameters—magnetic field strength, number of stimulations per day and duration—are systematically established to maximize the proliferation of multipotent mesenchymal stem cells up to 30% confirmed by WST-1 analysis.

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调整磁电刺激方法增强pvdf基纳米复合材料细胞增殖

提出了一种材料的组合，如pvdf基复合材料与10 wt %的CoFe2O4纳米颗粒和一种方法的ME刺激干细胞使用垂直移动低频（0.3 Hz）磁场具有给定的振幅。系统建立最佳刺激参数-磁场强度，每天刺激次数和持续时间-以最大限度地提高多能间充质干细胞的增殖，WST-1分析证实可达30%。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nanotechnologies in Russia NANOSCIENCE & NANOTECHNOLOGY-

CiteScore

1.20

自引率

0.00%

发文量

期刊介绍： Nanobiotechnology Reports publishes interdisciplinary research articles on fundamental aspects of the structure and properties of nanoscale objects and nanomaterials, polymeric and bioorganic molecules, and supramolecular and biohybrid complexes, as well as articles that discuss technologies for their preparation and processing, and practical implementation of products, devices, and nature-like systems based on them. The journal publishes original articles and reviews that meet the highest scientific quality standards in the following areas of science and technology studies: self-organizing structures and nanoassemblies; nanostructures, including nanotubes; functional and structural nanomaterials; polymeric, bioorganic, and hybrid nanomaterials; devices and products based on nanomaterials and nanotechnology; nanobiology and genetics, and omics technologies; nanobiomedicine and nanopharmaceutics; nanoelectronics and neuromorphic computing systems; neurocognitive systems and technologies; nanophotonics; natural science methods in a study of cultural heritage items; metrology, standardization, and monitoring in nanotechnology.