Pharmaceutical application of beta-glucan: a comprehensive overview

IF 3 Q2 PHARMACOLOGY & PHARMACY

Future Journal of Pharmaceutical Sciences Pub Date : 2025-06-20 DOI:10.1186/s43094-025-00835-1

Pooja Anand Mundada, Hitendra Shaligram Mahajan

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引用次数: 0

Abstract

Background

Beta-glucan (BG) is a diverse group of polysaccharides widely distributed in nature, including fungi, algae, bacteria, and cereals. Due to its unique physicochemical and biological properties, BG has gained significant attention in various fields, such as pharmaceuticals, cosmetics, nutraceuticals, and agriculture.

Main body

This article provides a comprehensive overview of BG’s applications and highlights their potential benefits in pharmaceuticals. BG has demonstrated significant potential as an immunomodulatory agent in the pharmaceutical field. They can stimulate the immune system, enhance the activity of macrophages, and increase the production of cytokines. This makes BG valuable in developing immunotherapeutic drugs, vaccine adjuvants, and wound-healing formulations. Additionally, BG has shown anticancer properties and has been investigated as a potential cancer prevention and treatment agent.

Conclusion

Overall, this overview highlights the diverse applications of BG in pharmaceuticals. Their functional and bioactive properties make them versatile ingredients in pharmaceuticals. The understanding of BG structure–function relationships and their mechanisms of action continues to expand, paving the way for future novel and innovative uses of these polysaccharides.

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-葡聚糖的医药应用综述

β -葡聚糖（BG）是一种广泛分布于自然界的多种多糖，包括真菌、藻类、细菌和谷物。由于其独特的物理化学和生物特性，BG在制药、化妆品、营养食品和农业等各个领域受到了极大的关注。这篇文章提供了BG应用的全面概述，并强调了它们在制药领域的潜在好处。作为一种免疫调节剂，BG在制药领域已显示出巨大的潜力。它们可以刺激免疫系统，增强巨噬细胞的活性，增加细胞因子的产生。这使得BG在开发免疫治疗药物、疫苗佐剂和伤口愈合制剂方面具有价值。此外，BG已显示出抗癌特性，并已被研究为潜在的癌症预防和治疗剂。总之，这篇综述强调了BG在药物中的不同应用。它们的功能性和生物活性使它们成为药物中的多种成分。对BG结构-功能关系及其作用机制的理解不断扩大，为未来这些多糖的新颖和创新用途铺平了道路。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Future Journal of Pharmaceutical Sciences PHARMACOLOGY & PHARMACY-

自引率

0.00%

发文量

审稿时长

23 weeks

期刊介绍： Future Journal of Pharmaceutical Sciences (FJPS) is the official journal of the Future University in Egypt. It is a peer-reviewed, open access journal which publishes original research articles, review articles and case studies on all aspects of pharmaceutical sciences and technologies, pharmacy practice and related clinical aspects, and pharmacy education. The journal publishes articles covering developments in drug absorption and metabolism, pharmacokinetics and dynamics, drug delivery systems, drug targeting and nano-technology. It also covers development of new systems, methods and techniques in pharmacy education and practice. The scope of the journal also extends to cover advancements in toxicology, cell and molecular biology, biomedical research, clinical and pharmaceutical microbiology, pharmaceutical biotechnology, medicinal chemistry, phytochemistry and nutraceuticals.