Novel Schiff Base Functionalized Cu(II) onto L-dopa/Al2O3-Fe3O4 as an Efficient Catalyst for One Pot Synthesis of 1,4-Disubstituted-1,2,3-Triazoles using Boronic Acids in Benign Reaction Media

Abstract

This study presents the synthesis of a novel Schiff base functionalized Cu(II) onto L-dopaSB/Al₂O₃-Fe₃O₄ as an efficient magnetic nanocomposite (Cu@L-dopaSB/Al₂O₃-Fe₃O₄). The synthesized catalyst has been characterized using various techniques, including HR-SEM, EDX, TEM, XRD, BET, FTIR, ICP-AES, CHN, TGA, and VSM analysis. The catalyst demonstrated excellent catalytic activity for the one-pot synthesis of 1,4-disubstituted 1,2,3-triazoles from aryl/alkyl boronic acids under sustainable reaction conditions. Since the catalyst is magnetic, it can be easily recovered using an external magnet and reused for up to six consecutive runs without any significant changes in catalytic activity, hence, making it eco-friendly and economical.

Graphical Abstract

Novel Schiff base functionalized Cu@L-dopaSB/Al₂O₃-Fe₃O₄ magnetic nanocomposite serves as an efficient magnetic catalyst for the three-component, one-pot click reaction for the synthesis of 1,4-disubstituted-1,2,3-triazoles using aryl/alkyl boronic acids under sustainable reaction conditions.