Cerium-doped calcium phosphate materials for bone tissue engineering

IF 1.7 4区 化学 Q3 CHEMISTRY, MULTIDISCIPLINARY
V. K. Besprozvannykh, I. E. Nifant’ev, A. N. Tavtorkin, P. V. Ivchenko
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引用次数: 0

Abstract

Cerium-doped calcium phosphate (Ce-CP) ceramics represent a promising class of materials for bone tissue engineering, due to their biocompatibility, and possess antioxidant, antibacterial, and osteoinductive properties. Furthermore, the application of Ce-CP ceramics in tissue-engineered constructs and materials may accelerate vascular regeneration and growth, which is critically important for the development of new methods and approaches in tissue engineering. This study is the first comprehensive review of Ce-CP ceramics, addressing possible pathways of Ce incorporation into calcium phosphate and methods of synthesis and structural characterization of Ce-CPs. Data on their biocompatibility and toxicity are summarized. The future potential of Ce-CPs in bone tissue engineering is considered.

骨组织工程用掺铈磷酸钙材料
铈掺杂磷酸钙(Ce-CP)陶瓷由于其生物相容性、抗氧化、抗菌和骨诱导等特性,在骨组织工程中具有很好的应用前景。此外,Ce-CP陶瓷在组织工程结构和材料中的应用可能会加速血管的再生和生长,这对组织工程新方法和新途径的发展至关重要。本研究首次对Ce- cp陶瓷进行了全面的综述,阐述了Ce与磷酸钙结合的可能途径以及Ce- cp的合成方法和结构表征。综述了它们的生物相容性和毒性。展望了Ce-CPs在骨组织工程中的应用前景。
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来源期刊
Russian Chemical Bulletin
Russian Chemical Bulletin 化学-化学综合
CiteScore
2.70
自引率
47.10%
发文量
257
审稿时长
3-8 weeks
期刊介绍: Publishing nearly 500 original articles a year, by leading Scientists from Russia and throughout the world, Russian Chemical Bulletin is a prominent international journal. The coverage of the journal spans practically all areas of fundamental chemical research and is presented in five sections: General and Inorganic Chemistry; Physical Chemistry; Organic Chemistry; Organometallic Chemistry; Chemistry of Natural Compounds and Bioorganic Chemistry.
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