V. K. Besprozvannykh, I. E. Nifant’ev, A. N. Tavtorkin, P. V. Ivchenko
{"title":"Cerium-doped calcium phosphate materials for bone tissue engineering","authors":"V. K. Besprozvannykh, I. E. Nifant’ev, A. N. Tavtorkin, P. V. Ivchenko","doi":"10.1007/s11172-024-4647-2","DOIUrl":null,"url":null,"abstract":"<div><p>Cerium-doped calcium phosphate (Ce-CP) ceramics represent a promising class of materials for bone tissue engineering, due to their biocompatibility, and possess antioxidant, antibacterial, and osteoinductive properties. Furthermore, the application of Ce-CP ceramics in tissue-engineered constructs and materials may accelerate vascular regeneration and growth, which is critically important for the development of new methods and approaches in tissue engineering. This study is the first comprehensive review of Ce-CP ceramics, addressing possible pathways of Ce incorporation into calcium phosphate and methods of synthesis and structural characterization of Ce-CPs. Data on their biocompatibility and toxicity are summarized. The future potential of Ce-CPs in bone tissue engineering is considered.</p></div>","PeriodicalId":756,"journal":{"name":"Russian Chemical Bulletin","volume":"74 6","pages":"1505 - 1540"},"PeriodicalIF":1.7000,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Russian Chemical Bulletin","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s11172-024-4647-2","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Cerium-doped calcium phosphate (Ce-CP) ceramics represent a promising class of materials for bone tissue engineering, due to their biocompatibility, and possess antioxidant, antibacterial, and osteoinductive properties. Furthermore, the application of Ce-CP ceramics in tissue-engineered constructs and materials may accelerate vascular regeneration and growth, which is critically important for the development of new methods and approaches in tissue engineering. This study is the first comprehensive review of Ce-CP ceramics, addressing possible pathways of Ce incorporation into calcium phosphate and methods of synthesis and structural characterization of Ce-CPs. Data on their biocompatibility and toxicity are summarized. The future potential of Ce-CPs in bone tissue engineering is considered.
期刊介绍:
Publishing nearly 500 original articles a year, by leading Scientists from Russia and throughout the world, Russian Chemical Bulletin is a prominent international journal. The coverage of the journal spans practically all areas of fundamental chemical research and is presented in five sections:
General and Inorganic Chemistry;
Physical Chemistry;
Organic Chemistry;
Organometallic Chemistry;
Chemistry of Natural Compounds and Bioorganic Chemistry.