{"title":"Empyema caused by Parvimonas micra: A case report","authors":"Yali Qiu , Xiwei Zhang , Ying Feng , Lifei Wang","doi":"10.1016/j.hmedic.2025.100354","DOIUrl":null,"url":null,"abstract":"<div><div><em>Parvimonas Micra</em>, a Gram-positive anaerobic coccus, has been implicated in a range of infectious conditions affecting immunocompromised individuals, particularly those with diabetes or malignancies. It is considered a key pathogen associated with chronic apical periodontitis and has been identified in several non-oral infections, including purulent spondylitis, infective endocarditis, and discitis. However, there is a paucity of comprehensive and systematic research on the pathogenesis of <em>Parvimonas micra</em>-induced empyema. This case report aims to elucidate the mechanisms underlying empyema development in patients with type 2 diabetes mellitus, to enhance clinical diagnostic accuracy and therapeutic strategies for such cases.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"14 ","pages":"Article 100354"},"PeriodicalIF":0.0000,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2949918625001998","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Parvimonas Micra, a Gram-positive anaerobic coccus, has been implicated in a range of infectious conditions affecting immunocompromised individuals, particularly those with diabetes or malignancies. It is considered a key pathogen associated with chronic apical periodontitis and has been identified in several non-oral infections, including purulent spondylitis, infective endocarditis, and discitis. However, there is a paucity of comprehensive and systematic research on the pathogenesis of Parvimonas micra-induced empyema. This case report aims to elucidate the mechanisms underlying empyema development in patients with type 2 diabetes mellitus, to enhance clinical diagnostic accuracy and therapeutic strategies for such cases.