Neuraxial Compared With General Anesthesia on Postoperative Outcomes After Hip Arthroplasty for Geriatric Hip Fracture: Results From a National Database.
{"title":"Neuraxial Compared With General Anesthesia on Postoperative Outcomes After Hip Arthroplasty for Geriatric Hip Fracture: Results From a National Database.","authors":"Fanqiang Meng,Yuqing Wang,Liusong Shen,Junzhi Sheng,Huizhong Long,Hu Chen,Xiaoxiao Li,Dongxing Xie,Xiang Ding","doi":"10.1213/ane.0000000000007758","DOIUrl":null,"url":null,"abstract":"BACKGROUND\r\nAnesthesia choice affects hip fracture surgery outcomes. However, limited evidence exists regarding the impact of neuraxial anesthesia (NA) versus general anesthesia (GA) on postoperative outcomes, specifically in hip arthroplasty for fracture. The purpose of this study was to compare 30-day readmission, in-hospital complications, hospitalization charges, and length of stay between the elderly who received NA and GA during this procedure.\r\n\r\nMETHODS\r\nThe Hospital Quality Monitoring System was analyzed for patients undergoing hip arthroplasty for geriatric hip fracture (≥60 years of age) between 2013 and 2019. After adjusting for potential confounders with propensity score matching, logistic regression and linear regression analyses were conducted to compare NA with GA in terms of 30-day readmission rates and causes, in-hospital complications (including in-hospital mortality, pulmonary embolism, deep vein thrombosis, wound infection, and blood transfusion), hospitalization charges, and length of stay.\r\n\r\nRESULTS\r\nOf the 90,745 patients undergoing hip arthroplasty for geriatric hip fracture during the study period (40,551 [44.7%] for NA, 50,194 [55.3%] for GA), a total of 62,022 patients (31,011 propensity score-matched pairs) were included after study exclusions and propensity score matching. NA was significantly associated with a lower incidence of 30-day readmission (4.60% vs 4.97%, odds ratio [OR] = 0.92, 95% confidence interval [CI], 0.86-0.99, P =.032) and fewer genitourinary system complaints (0.18% vs 0.26%, OR = 0.70, 95% CI, 0.50-0.97, P =.035) for readmission compared with GA. The incidence of in-hospital mortality (0.41% vs 0.64%, OR = 0.64, 95% CI, 0.52-0.81, P <.001), deep vein thrombosis (1.84% vs 2.57%, OR = 0.71, 95% CI, 0.64-0.79, P <.001), and pulmonary embolism (0.22% vs 0.38%, OR = 0.58, 95% CI, 0.43-0.79, P <.001) was also lower for NA compared with GA. Moreover, patients with NA had decreased charges (49,851.8 Chinese Yuan [CNY] vs 54,754.8 CNY, P <.001) relative to GA. The length of stay did not differ significantly between NA and GA (13.7 days vs 13.8 days, P =.217).\r\n\r\nCONCLUSIONS\r\nIn geriatric patients undergoing hip arthroplasty for hip fracture, NA is associated with lower rates of 30-day readmission, fewer readmission caused by genitourinary system complaints, reduced complications, and decreased hospitalization charges compared to GA.","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"18 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Anesthesia & Analgesia","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1213/ane.0000000000007758","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
BACKGROUND
Anesthesia choice affects hip fracture surgery outcomes. However, limited evidence exists regarding the impact of neuraxial anesthesia (NA) versus general anesthesia (GA) on postoperative outcomes, specifically in hip arthroplasty for fracture. The purpose of this study was to compare 30-day readmission, in-hospital complications, hospitalization charges, and length of stay between the elderly who received NA and GA during this procedure.
METHODS
The Hospital Quality Monitoring System was analyzed for patients undergoing hip arthroplasty for geriatric hip fracture (≥60 years of age) between 2013 and 2019. After adjusting for potential confounders with propensity score matching, logistic regression and linear regression analyses were conducted to compare NA with GA in terms of 30-day readmission rates and causes, in-hospital complications (including in-hospital mortality, pulmonary embolism, deep vein thrombosis, wound infection, and blood transfusion), hospitalization charges, and length of stay.
RESULTS
Of the 90,745 patients undergoing hip arthroplasty for geriatric hip fracture during the study period (40,551 [44.7%] for NA, 50,194 [55.3%] for GA), a total of 62,022 patients (31,011 propensity score-matched pairs) were included after study exclusions and propensity score matching. NA was significantly associated with a lower incidence of 30-day readmission (4.60% vs 4.97%, odds ratio [OR] = 0.92, 95% confidence interval [CI], 0.86-0.99, P =.032) and fewer genitourinary system complaints (0.18% vs 0.26%, OR = 0.70, 95% CI, 0.50-0.97, P =.035) for readmission compared with GA. The incidence of in-hospital mortality (0.41% vs 0.64%, OR = 0.64, 95% CI, 0.52-0.81, P <.001), deep vein thrombosis (1.84% vs 2.57%, OR = 0.71, 95% CI, 0.64-0.79, P <.001), and pulmonary embolism (0.22% vs 0.38%, OR = 0.58, 95% CI, 0.43-0.79, P <.001) was also lower for NA compared with GA. Moreover, patients with NA had decreased charges (49,851.8 Chinese Yuan [CNY] vs 54,754.8 CNY, P <.001) relative to GA. The length of stay did not differ significantly between NA and GA (13.7 days vs 13.8 days, P =.217).
CONCLUSIONS
In geriatric patients undergoing hip arthroplasty for hip fracture, NA is associated with lower rates of 30-day readmission, fewer readmission caused by genitourinary system complaints, reduced complications, and decreased hospitalization charges compared to GA.
背景:麻醉选择影响髋部骨折手术结果。然而,关于神经轴麻醉(NA)与全身麻醉(GA)对术后结果的影响,特别是在骨折髋关节置换术中,证据有限。本研究的目的是比较在此过程中接受NA和GA的老年人的30天再入院、住院并发症、住院费用和住院时间。方法对2013 - 2019年接受髋关节置换术治疗老年髋部骨折(≥60岁)患者的医院质量监测系统进行分析。通过倾向评分匹配调整潜在混杂因素后,进行logistic回归和线性回归分析,比较NA和GA在30天再入院率和原因、院内并发症(包括院内死亡率、肺栓塞、深静脉血栓形成、伤口感染和输血)、住院费用和住院时间方面的差异。结果在研究期间,90,745例老年髋部骨折行髋关节置换术的患者(40,551例[44.7%],50,194例[55.3%]),经研究排除和倾向评分匹配后,共纳入62,022例患者(31,011对倾向评分匹配)。与GA相比,NA与较低的30天再入院发生率(4.60% vs 4.97%,优势比[OR] = 0.92, 95%可信区间[CI], 0.86-0.99, P = 0.032)和较低的泌尿生殖系统再入院发生率(0.18% vs 0.26%, OR = 0.70, 95% CI, 0.50-0.97, P = 0.035)显著相关。住院死亡率(0.41% vs 0.64%, OR = 0.64, 95% CI, 0.52-0.81, P <.001)、深静脉血栓形成(1.84% vs 2.57%, OR = 0.71, 95% CI, 0.64-0.79, P <.001)和肺栓塞(0.22% vs 0.38%, OR = 0.58, 95% CI, 0.43-0.79, P <.001)的发生率也低于GA。此外,NA组患者的收费较GA组降低(49,851.8元人民币vs 54,754.8元人民币,P < 0.001)。住院时间在NA和GA之间没有显著差异(13.7天vs 13.8天,P = 0.217)。结论在髋部骨折行髋关节置换术的老年患者中,与GA相比,NA具有更低的30天再入院率、更少的泌尿生殖系统疾病引起的再入院率、更少的并发症和更低的住院费用。